TY - JOUR
T1 - Draft genome sequence of an aminoglycoside-resistant RmtG-producing Pseudomonas aeruginosa ST235 isolated from a cystic fibrosis patient
AU - Bueno, Maria Fernanda C.
AU - Francisco, Gabriela Rodrigues
AU - Cerdeira, Louise
AU - Ienne, Susan
AU - Souza, Tiago A.
AU - Lincopan, Nilton
AU - de Oliveira Garcia, Doroti
PY - 2017/3/1
Y1 - 2017/3/1
N2 - Cystic fibrosis (CF) patients are often chronically colonised or infected by non-fermenting Gram-negative bacilli, with Pseudomonas aeruginosa being the most prevalent. In this study, we report the draft genome sequence of a multidrug-resistant P. aeruginosa strain belonging to sequence type ST235, isolated from the respiratory tract of a CF patient with chronic colonisation. Whole-genome sequencing analysis revealed a 6.7 Mb genome size and the presence of 12 antibiotic resistance genes, including the rmtG gene conferring high-level aminoglycoside resistance, located on the chromosome.
AB - Cystic fibrosis (CF) patients are often chronically colonised or infected by non-fermenting Gram-negative bacilli, with Pseudomonas aeruginosa being the most prevalent. In this study, we report the draft genome sequence of a multidrug-resistant P. aeruginosa strain belonging to sequence type ST235, isolated from the respiratory tract of a CF patient with chronic colonisation. Whole-genome sequencing analysis revealed a 6.7 Mb genome size and the presence of 12 antibiotic resistance genes, including the rmtG gene conferring high-level aminoglycoside resistance, located on the chromosome.
KW - Brazil
KW - Cystic fibrosis
KW - Pseudomonas aeruginosa
KW - RmtG
KW - WGS
UR - http://www.scopus.com/inward/record.url?scp=85009088493&partnerID=8YFLogxK
U2 - 10.1016/j.jgar.2016.11.005
DO - 10.1016/j.jgar.2016.11.005
M3 - Comment / Debate
C2 - 28082143
AN - SCOPUS:85009088493
SN - 2213-7165
VL - 8
SP - 106
EP - 107
JO - Journal of Global Antimicrobial Resistance
JF - Journal of Global Antimicrobial Resistance
ER -