Dr. Hellquist, et al reply

Anna Hellquist, Tiina M. Järvinen, Sari Koskenmies, Marco Zucchelli, Christina Orsmark-Pietras, Linda Berglind, Jaana Panelius, Taina Hasan, Heikki Julkunen, Mauro D'Amato, Ulpu Saarialho-Kere, Juha Kere

Research output: Contribution to journalLetterOther


We read with interest the letter of Suarez-Gestal, et al1, and we believe that it is useful to briefly discuss possible causes of differences between our study2, which reported an interaction between the TYK2 and IRF5 genes, and the report of Suarez-Gestal, et al. It is a common observation that replicating even single-gene association results in complex disorders is not always easy, and largely the same causes that may explain these differences also apply to gene-gene interaction studies.
Original languageEnglish
Number of pages1
JournalThe Journal of Rheumatology
Issue number3
Publication statusPublished - 1 Mar 2010
Externally publishedYes

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