TY - JOUR
T1 - Doxycycline and Sitafloxacin Combination Therapy for Treating Highly Resistant Mycoplasma genitalium
AU - Durukan, Duygu
AU - Doyle, Michelle
AU - Murray, Gerald
AU - Bodiyabadu, Kaveesha
AU - Vodstrcil, Lenka
AU - Chow, Eric P.F.
AU - Jensen, Jorgen S.
AU - Fairley, Christopher K.
AU - Aguirre, Ivette
AU - Bradshaw, Catriona S.
PY - 2020/8
Y1 - 2020/8
N2 - Antimicrobial-resistant Mycoplasma genitalium is becoming increasingly common and creating major treatment challenges. We present early data on combination therapy with doxycycline and sitafloxacin to treat highly resistant M. genitalium. We found the regimen was well tolerated and cured 11/12 infections that had failed prior regimens with moxifloxacin and pristinamycin.
AB - Antimicrobial-resistant Mycoplasma genitalium is becoming increasingly common and creating major treatment challenges. We present early data on combination therapy with doxycycline and sitafloxacin to treat highly resistant M. genitalium. We found the regimen was well tolerated and cured 11/12 infections that had failed prior regimens with moxifloxacin and pristinamycin.
KW - AMR
KW - antimicrobial resistance
KW - doxycycline
KW - dual-class resistance
KW - macrolide resistance
KW - multidrug resistance
KW - Mycoplasma genitalium
KW - quinolone resistance
KW - sexually transmitted infections
KW - sitafloxacin
UR - http://www.scopus.com/inward/record.url?scp=85088351246&partnerID=8YFLogxK
U2 - 10.3201/eid2608.191806
DO - 10.3201/eid2608.191806
M3 - Article
C2 - 32687029
AN - SCOPUS:85088351246
VL - 26
SP - 1870
EP - 1874
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
SN - 1080-6040
IS - 8
ER -