Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the benefits and harms of dose reduction or discontinuation of disease-modifying anti-rheumatic drugs in children and young people with clinically inactive juvenile idiopathic arthritis. This is a common protocol for two separate reviews: one on systemic onset juvenile idiopathic arthritis and one on non-systemic juvenile idiopathic arthritis. A secondary objective is to keep the evidence current, using a living systematic review approach.