TY - JOUR
T1 - Dose distributions in SBRT of lung tumors
T2 - Comparison between two different treatment planning algorithms and Monte-Carlo simulation including breathing motions
AU - Lax, Ingmar
AU - Panettieri, Vanessa
AU - Wennberg, Berit
AU - Duch, Maria Amor
AU - Näslund, Ingemar
AU - Baumann, Pia
AU - Gagliardi, Giovanna
N1 - Funding Information:
This work was supported by grants from the Cancer Society in Stockholm.
PY - 2006/9/1
Y1 - 2006/9/1
N2 - In stereotactic body radiotherapy (SBRT) of lung tumors, dosimetric problems arise from: 1) the limited accuracy in the dose calculation algorithms in treatment planning systems, and 2) the motions with the respiration of the tumor during treatment. Longitudinal dose distributions have been calculated with Monte Carlo simulation (MC), a pencil beam algorithm (PB) and a collapsed cone algorithm (CC) for two spherical lung tumors (2 cm and 5 cm diameter) in lung tissue, in a phantom situation. Respiratory motions were included by a convolution method, which was validated. In the static situation, the PB significantly overestimates the dose, relative to MC, while the CC gives a relatively accurate estimate. Four different respiratory motion patterns were included in the dose calculation with the MC. A "narrowing" of the longitudinal dose profile of up to 20 mm (at about 90% dose level) is seen relative the static dose profile calculated with the PB.
AB - In stereotactic body radiotherapy (SBRT) of lung tumors, dosimetric problems arise from: 1) the limited accuracy in the dose calculation algorithms in treatment planning systems, and 2) the motions with the respiration of the tumor during treatment. Longitudinal dose distributions have been calculated with Monte Carlo simulation (MC), a pencil beam algorithm (PB) and a collapsed cone algorithm (CC) for two spherical lung tumors (2 cm and 5 cm diameter) in lung tissue, in a phantom situation. Respiratory motions were included by a convolution method, which was validated. In the static situation, the PB significantly overestimates the dose, relative to MC, while the CC gives a relatively accurate estimate. Four different respiratory motion patterns were included in the dose calculation with the MC. A "narrowing" of the longitudinal dose profile of up to 20 mm (at about 90% dose level) is seen relative the static dose profile calculated with the PB.
UR - http://www.scopus.com/inward/record.url?scp=33748881814&partnerID=8YFLogxK
U2 - 10.1080/02841860600900050
DO - 10.1080/02841860600900050
M3 - Article
C2 - 16982567
AN - SCOPUS:33748881814
VL - 45
SP - 978
EP - 988
JO - Acta Oncologica
JF - Acta Oncologica
SN - 0284-186X
IS - 7
ER -