TY - JOUR
T1 - Does type 1 diabetes mellitus affect Achilles tendon response to a 10 km run? A case control study
AU - Wong, Andrea Mei Yim
AU - Docking, Sean
AU - Cook, Jillianne Leigh
AU - Gaida, James Edmund
PY - 2015
Y1 - 2015
N2 - Background: Achilles tendon structure deteriorates 2-days after maximal loading in elite athletes. The load-response behaviour of tendons may be altered in type 1 diabetes mellitus (T1DM) as hyperglycaemia accelerates collagen cross-linking. This study compared Achilles tendon load-response in participants with T1DM and controls. Methods: Achilles tendon structure was quantified at day-0, day-2 and day-4 after a 10 km run. Ultrasound tissue characterisation (UTC) measures tendon structural integrity by classifying pixels as echo-type I, II, III or IV. Echo-type I has the most aligned collagen fibrils and IV has the least.
AB - Background: Achilles tendon structure deteriorates 2-days after maximal loading in elite athletes. The load-response behaviour of tendons may be altered in type 1 diabetes mellitus (T1DM) as hyperglycaemia accelerates collagen cross-linking. This study compared Achilles tendon load-response in participants with T1DM and controls. Methods: Achilles tendon structure was quantified at day-0, day-2 and day-4 after a 10 km run. Ultrasound tissue characterisation (UTC) measures tendon structural integrity by classifying pixels as echo-type I, II, III or IV. Echo-type I has the most aligned collagen fibrils and IV has the least.
UR - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641391/pdf/12891_2015_Article_803.pdf
U2 - 10.1186/s12891-015-0803-z
DO - 10.1186/s12891-015-0803-z
M3 - Article
VL - 16
SP - 1
EP - 7
JO - BMC Musculoskeletal Disorders
JF - BMC Musculoskeletal Disorders
SN - 1471-2474
IS - 1 (Art. No: 345)
ER -
