Does the autonomic nervous system contribute to the initiation and progression of prostate cancer?

Sabatino Ventura, Bronwyn Anne Evans

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)


In the July 12 issue of Science magazine, researchers from the Albert Einstein College of Medicine, the Mount Sinai School of Medicine, the Durham VA Medical Centre and Duke University published an elegant study demonstrating that the sympathetic nervous system, acting through ?2 and ?3-adrenoceptors in the prostate, plays an important role in the initiation of prostate cancer, while the parasympathetic nervous system plays a role in the dissemination of tumour metastases via M1 muscarinic receptors. These findings are significant because they indicate that receptors associated with the autonomic nervous system may be viable targets for prostate cancer therapy.
Original languageEnglish
Pages (from-to)715 - 716
Number of pages2
JournalAsian Journal of Andrology
Issue number6
Publication statusPublished - 2013

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