Projects per year
This prospective controlled study examined long-term trajectories of neuropsychological performance in individuals with traumatic brain injury (TBI) compared to healthy controls, and the impact of IQ, age at injury, time since injury, and injury severity on change over time. Fifty-three individuals with moderate to severe TBI (60.37% male; M = 59.77 yrs, SD= 14.03), and 26 controls (46.15% male; M = 63.96 yrs, SD= 14.42) were studied prospectively (M = 12.72 yrs between assessments). Participants completed measures of premorbid IQ (Weschler Test of Adult Reading), processing speed (Digit Symbol Coding Test), working memory (Digit Span Backwards), memory (Rey Auditory Verbal Learning Test) and executive function (Trail Making Test Part B; Hayling Errors), at a mean of 10.62 yrs (Initial) and 23.91 yrs (Follow-Up) post injury. Individuals with TBI did not show a significantly greater decline in neuropsychological performance over time compared with demographically similar controls. There was no association between change over time with IQ, time since injury or injury severity. Being older at injury had a greater adverse impact on executive function at follow-up. In this small sample, a single moderate to severe TBI was not associated with ongoing cognitive decline up to three decades post injury. Changes in cognitive function were similar between the groups and likely reflect healthy aging.
- cognitive decline
- Traumatic brain injury
- 1 Finished
Traumatic Brain Injury, Post Traumatic Stress Disorder and the Risk of Neurodegenerative Disease: a study of tau and beta-amyloid accumulation, brain structure and function several decades after injury.
Rowe, C. C., McCrory, P., Ponsford, J., O'Donnell, M. L. & Hopwood, M.
1/01/17 → 31/12/19