Docking proteins

Tilman Brummer, Carsten Schmitz-Peiffer, Roger John Daly

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

Abstract

Docking proteins comprise a distinct category of intracellular, noncatalytic signalling protein, that function downstream of a variety of receptor and receptor-associated tyrosine kinases and regulate diverse physiological and pathological processes. The growth factor receptor bound 2-associated binder/Daughter of Sevenless, insulin receptor substrate, fibroblast growth factor receptor substrate 2 and downstream of tyrosine kinases protein families fall into this category. This minireview focuses on the structure, function and regulation of these proteins.
Original languageEnglish
Pages (from-to)4356 - 4369
Number of pages14
JournalThe FEBS Journal
Volume277
Issue number21
DOIs
Publication statusPublished - 2010
Externally publishedYes

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