DNA multilayer films on planar and colloidal supports: Sequential assembly of like-charged polyelectrolytes

Angus P.R. Johnston; Elizabeth S. Read; Frank Caruso

doi:10.1021/nl050608b

DNA multilayer films on planar and colloidal supports: Sequential assembly of like-charged polyelectrolytes

Angus P.R. Johnston
, Elizabeth S. Read
, Frank Caruso

Research output: Contribution to journal › Article › Research › peer-review

207 Citations (Scopus)

Abstract

Multilayer films comprising solely negatively charged polyelectrolytes were sequentially assembled based on DNA hybridization. Films prepared from alternating layers of two-block homopolymeric nucleotides (polyA ₂₀G₂₀/polyT₂₀C₂₀) grew linearly with increasing layer number, as verified by quartz crystal microgravimetry, UV-vis spectrophotometry and optical microscopy. Urea treatment of the films induced morphological changes, while exposure to low ionic strength solutions resulted in film disassembly. DNA multilayer films were also formed on silica particles, and DNA hollow capsules were obtained following dissolution of the template core.

Original language	English
Pages (from-to)	953-956
Number of pages	4
Journal	Nano Letters
Volume	5
Issue number	5
DOIs	https://doi.org/10.1021/nl050608b
Publication status	Published - 1 May 2005
Externally published	Yes

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10.1021/nl050608b

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abstract = "Multilayer films comprising solely negatively charged polyelectrolytes were sequentially assembled based on DNA hybridization. Films prepared from alternating layers of two-block homopolymeric nucleotides (polyA 20G20/polyT20C20) grew linearly with increasing layer number, as verified by quartz crystal microgravimetry, UV-vis spectrophotometry and optical microscopy. Urea treatment of the films induced morphological changes, while exposure to low ionic strength solutions resulted in film disassembly. DNA multilayer films were also formed on silica particles, and DNA hollow capsules were obtained following dissolution of the template core.",

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AU - Read, Elizabeth S.

AU - Caruso, Frank

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N2 - Multilayer films comprising solely negatively charged polyelectrolytes were sequentially assembled based on DNA hybridization. Films prepared from alternating layers of two-block homopolymeric nucleotides (polyA 20G20/polyT20C20) grew linearly with increasing layer number, as verified by quartz crystal microgravimetry, UV-vis spectrophotometry and optical microscopy. Urea treatment of the films induced morphological changes, while exposure to low ionic strength solutions resulted in film disassembly. DNA multilayer films were also formed on silica particles, and DNA hollow capsules were obtained following dissolution of the template core.

AB - Multilayer films comprising solely negatively charged polyelectrolytes were sequentially assembled based on DNA hybridization. Films prepared from alternating layers of two-block homopolymeric nucleotides (polyA 20G20/polyT20C20) grew linearly with increasing layer number, as verified by quartz crystal microgravimetry, UV-vis spectrophotometry and optical microscopy. Urea treatment of the films induced morphological changes, while exposure to low ionic strength solutions resulted in film disassembly. DNA multilayer films were also formed on silica particles, and DNA hollow capsules were obtained following dissolution of the template core.

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DO - 10.1021/nl050608b

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DNA multilayer films on planar and colloidal supports: Sequential assembly of like-charged polyelectrolytes

Abstract

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