DNA-mediated electrostatic assembly of gold nanoparticles into linear arrays by a simple drop-coating procedure

Murali Sastry, Ashavani Kumar, Suvarna Datar, C. V. Dharmadhikari, Krishna N. Ganesh

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84 Citations (Scopus)


The assembly of nanoparticles in topologically predefined superstructures is an important problem in the area of nanoscale architecture. In this letter, we demonstrate the electrostatic assembly of lysine-capped colloidal gold particles on drop-coated DNA films. Electrostatic interaction between the positive charges on the gold nanoparticles and the negative charges on the phosphate groups of the DNA template molecules leads to the assembly of the gold nanoparticles in linear superstructures. The use of DNA as templates for the assembly of nanoparticles shows promise for extension to more complex geometries through rational design of the DNA base sequences as well as in the realization of nanowires by stringing together metal nanoparticles.

Original languageEnglish
Pages (from-to)2943-2945
Number of pages3
JournalApplied Physics Letters
Issue number19
Publication statusPublished - 7 May 2001
Externally publishedYes

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