Abstract
Organisation of nanoparticles on structurally well-defined templates is a first step towards creating nanomachines. In this respect, nucleic acids are ideal structural templates and a variety of secondary structures realizable from DNA/RNA-e.g., duplexes, hairpins, triplexes, cruciforms, tetraplexes can be exploited to engineer nanoparticle organization at will. We have used oligonucleotides and their analogues such as phosphorothioates and peptide nucleic acids to electrostatically encapsulate cationic-capped gold nanoparticles. This article describes synthesis and characterization of DNA/PNA-gold nanoparticle composites using TEM and UV-Tm techniques. These types of assemblies may have potential for creating nanowires and lithographic circuits.
Original language | English |
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Pages (from-to) | 102-107 |
Number of pages | 6 |
Journal | Current Applied Physics |
Volume | 5 |
Issue number | 2 |
DOIs | |
Publication status | Published - Feb 2005 |
Externally published | Yes |
Event | Indo-Japan Workshop on Advanced Molecular Electronics 2003 - Kitakyushu, Japan Duration: 11 Dec 2003 → 12 Dec 2003 |
Keywords
- DNA
- DNA-gold nanoparticle interactions
- Nanoassemblies
- PNA