Abstract
DNA is a polyanionic molecule that can electrostatically interact with positively charged ligands. Interaction with surfactants such as CTAB leads to cooperative binding of detergent molecules through synergistic effects of electrostatic and hydrophobic forces. DNA can also form a monolayer at air-water interface with positively charged octylamine and nanoparticles with cationic lysine capped gold nanoparticles. Formation of such electrostatic composites of DNA has practical implications for developing DNA diagnostic systems and for lipidencapsulated DNA delivery systems.
| Original language | English |
|---|---|
| Pages (from-to) | 105-112 |
| Number of pages | 8 |
| Journal | Journal of the Indian Institute of Science |
| Volume | 82 |
| Issue number | 2 |
| Publication status | Published - Mar 2002 |
| Externally published | Yes |
Keywords
- DNA-gold nanoparticles
- DNA-Langmuir Blodgett monolayers
- DNA-surfactant interactions