Diuretic use in heart failure and outcomes

Thomas G von Lueder, Dan Atar, Henry Krum

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22 Citations (Scopus)


Diuretics are frequently administered to relieve congestive symptoms in patients with heart failure (HF). Despite their widespread use, prospective data on the potential of diuretics to modulate HF-related morbidity and mortality are scarce. Diuretic efficacy may be limited by adverse neurohormonal activation and by congestion-like symptoms that may occur in the absence of fluid overload. Herein, we review the current knowledge on diuretic use and outcomes in HF. ? 2013 American Society for Clinical Pharmacology and Therapeutics
Original languageEnglish
Pages (from-to)490 - 498
Number of pages9
JournalClinical Pharmacology & Therapeutics
Issue number4
Publication statusPublished - 2013

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