TY - JOUR
T1 - Diuretic use in heart failure and outcomes
AU - von Lueder, Thomas G
AU - Atar, Dan
AU - Krum, Henry
PY - 2013
Y1 - 2013
N2 - Diuretics are frequently administered to relieve congestive symptoms in patients with heart failure (HF). Despite their widespread use, prospective data on the potential of diuretics to modulate HF-related morbidity and mortality are scarce. Diuretic efficacy may be limited by adverse neurohormonal activation and by congestion-like symptoms that may occur in the absence of fluid overload. Herein, we review the current knowledge on diuretic use and outcomes in HF. ? 2013 American Society for Clinical Pharmacology and Therapeutics
AB - Diuretics are frequently administered to relieve congestive symptoms in patients with heart failure (HF). Despite their widespread use, prospective data on the potential of diuretics to modulate HF-related morbidity and mortality are scarce. Diuretic efficacy may be limited by adverse neurohormonal activation and by congestion-like symptoms that may occur in the absence of fluid overload. Herein, we review the current knowledge on diuretic use and outcomes in HF. ? 2013 American Society for Clinical Pharmacology and Therapeutics
UR - http://www.nature.com/clpt/journal/v94/n4/pdf/clpt2013140a.pdf
U2 - 10.1038/clpt.2013.140
DO - 10.1038/clpt.2013.140
M3 - Article
VL - 94
SP - 490
EP - 498
JO - Clinical Pharmacology & Therapeutics
JF - Clinical Pharmacology & Therapeutics
SN - 0009-9236
IS - 4
ER -