Discovery of 2-(2-Benzoxazoyl amino)-4-aryl-5-cyanopyrimidine as negative allosteric modulators (NAMs) of metabotropic glutamate receptor 5 (mGlu 5): from an artificial neural network virtual screen to an in vivo tool compound

Ralf Mueller, Eric S Dawson, Jens Meiler, Alice L Rodriguez, Brian A Chauder, Brittney S Bates, Andrew S Felts, Jeffrey P Lamb, Usha N Menon, Sataywan B Jadhav, Alexander S Kane, Carrie K Jones, Karen Joan Gregory, Colleen M Niswender, Peter Jeffrey Conn, Cnristopher M Olsen, Danny G Winder, Kyle A Emmitte, Craig W Lindsley

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)
Original languageEnglish
Pages (from-to)406 - 414
Number of pages9
JournalChemMedChem
Volume7
Issue number3
DOIs
Publication statusPublished - 2012

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