Direct antiatherosclerotic effects of PPAR agonists

Research output: Contribution to journalReview ArticleOtherpeer-review

26 Citations (Scopus)

Abstract

It is anticipated that the antiatherosclerotic effects of PPAR agonists observed in experimental studies will translate into reduced cardiovascular events. This promise is yet to be realized in short-to-medium term studies. Given the central role of the PPAR in gene regulation, particularly in metabolic states, it is possible that more targeted modulation of PPAR signalling may hold many rewards for the prevention of atherosclerosis.

Original languageEnglish
Pages (from-to)24-29
Number of pages6
JournalCurrent Opinion in Lipidology
Volume20
Issue number1
DOIs
Publication statusPublished - Feb 2009
Externally publishedYes

Cite this