TY - JOUR
T1 - Diffusive Mobile MC With Absorbing Receivers
T2 - Stochastic Analysis and Applications
AU - Cao, Trang Ngoc
AU - Ahmadzadeh, Arman
AU - Jamali, Vahid
AU - Wicke, Wayan
AU - Yeoh, Phee Lep
AU - Evans, Jamie
AU - Schober, Robert
N1 - Funding Information:
This work was supported in part by the Diane Lemaire Scholarship of the Melbourne School of Engineering, the Australian Research Council Discovery Project under Grant DP190100770, in part by the Emerging Fields Initiative of the Friedrich-Alexander-Universität Erlangen-Nürnberg, and in part by the STAEDTLER Stiftung.
Publisher Copyright:
© 2015 IEEE.
PY - 2019/11
Y1 - 2019/11
N2 - This paper presents a stochastic analysis of the time-variant channel impulse response (CIR) of a three dimensional diffusive mobile molecular communication (MC) system where the transmitter, the absorbing receiver, and the molecules can freely diffuse. In our analysis, we derive the mean, variance, probability density function (PDF), and cumulative distribution function (CDF) of the CIR. We also derive the PDF and CDF of the probability p that a released molecule is absorbed at the receiver during a given time period. The obtained analytical results are employed for the design of drug delivery and MC systems with imperfect channel state information. For the first application, we exploit the mean and variance of the CIR to optimize a controlled-release drug delivery system employing a mobile drug carrier. We evaluate the performance of the proposed release design based on the PDF and CDF of the CIR. We demonstrate significant savings in the amount of released drugs compared to a constant-release scheme and reveal the necessity of accounting for the drug-carrier's mobility to ensure reliable drug delivery. For the second application, we exploit the PDF of the distance between the mobile transceivers and the CDF of p to optimize three design parameters of an MC system employing on-off keying modulation and threshold detection. Specifically, we optimize the detection threshold at the receiver, the release profile at the transmitter, and the time duration of a bit frame. We show that the proposed optimal designs can significantly improve the system performance in terms of the bit error rate and the efficiency of molecule usage.
AB - This paper presents a stochastic analysis of the time-variant channel impulse response (CIR) of a three dimensional diffusive mobile molecular communication (MC) system where the transmitter, the absorbing receiver, and the molecules can freely diffuse. In our analysis, we derive the mean, variance, probability density function (PDF), and cumulative distribution function (CDF) of the CIR. We also derive the PDF and CDF of the probability p that a released molecule is absorbed at the receiver during a given time period. The obtained analytical results are employed for the design of drug delivery and MC systems with imperfect channel state information. For the first application, we exploit the mean and variance of the CIR to optimize a controlled-release drug delivery system employing a mobile drug carrier. We evaluate the performance of the proposed release design based on the PDF and CDF of the CIR. We demonstrate significant savings in the amount of released drugs compared to a constant-release scheme and reveal the necessity of accounting for the drug-carrier's mobility to ensure reliable drug delivery. For the second application, we exploit the PDF of the distance between the mobile transceivers and the CDF of p to optimize three design parameters of an MC system employing on-off keying modulation and threshold detection. Specifically, we optimize the detection threshold at the receiver, the release profile at the transmitter, and the time duration of a bit frame. We show that the proposed optimal designs can significantly improve the system performance in terms of the bit error rate and the efficiency of molecule usage.
KW - Absorbing receivers
KW - drug delivery
KW - mobile molecular communications
KW - stochastic channel modeling
KW - time-varying channels
UR - http://www.scopus.com/inward/record.url?scp=85082816624&partnerID=8YFLogxK
U2 - 10.1109/TMBMC.2020.2979364
DO - 10.1109/TMBMC.2020.2979364
M3 - Article
AN - SCOPUS:85082816624
SN - 2332-7804
VL - 5
SP - 84
EP - 99
JO - IEEE Transactions on Molecular, Biological, and Multi-Scale Communications
JF - IEEE Transactions on Molecular, Biological, and Multi-Scale Communications
IS - 2
ER -