Diffusive Mobile MC With Absorbing Receivers: Stochastic Analysis and Applications

Trang Ngoc Cao, Arman Ahmadzadeh, Vahid Jamali, Wayan Wicke, Phee Lep Yeoh, Jamie Evans, Robert Schober

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19 Citations (Scopus)

Abstract

This paper presents a stochastic analysis of the time-variant channel impulse response (CIR) of a three dimensional diffusive mobile molecular communication (MC) system where the transmitter, the absorbing receiver, and the molecules can freely diffuse. In our analysis, we derive the mean, variance, probability density function (PDF), and cumulative distribution function (CDF) of the CIR. We also derive the PDF and CDF of the probability p that a released molecule is absorbed at the receiver during a given time period. The obtained analytical results are employed for the design of drug delivery and MC systems with imperfect channel state information. For the first application, we exploit the mean and variance of the CIR to optimize a controlled-release drug delivery system employing a mobile drug carrier. We evaluate the performance of the proposed release design based on the PDF and CDF of the CIR. We demonstrate significant savings in the amount of released drugs compared to a constant-release scheme and reveal the necessity of accounting for the drug-carrier's mobility to ensure reliable drug delivery. For the second application, we exploit the PDF of the distance between the mobile transceivers and the CDF of p to optimize three design parameters of an MC system employing on-off keying modulation and threshold detection. Specifically, we optimize the detection threshold at the receiver, the release profile at the transmitter, and the time duration of a bit frame. We show that the proposed optimal designs can significantly improve the system performance in terms of the bit error rate and the efficiency of molecule usage.

Original languageEnglish
Pages (from-to)84-99
Number of pages16
JournalIEEE Transactions on Molecular, Biological, and Multi-Scale Communications
Volume5
Issue number2
DOIs
Publication statusPublished - Nov 2019
Externally publishedYes

Keywords

  • Absorbing receivers
  • drug delivery
  • mobile molecular communications
  • stochastic channel modeling
  • time-varying channels

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