Diffuse idiopathic skeletal hyperostosis and new bone formation in male gouty subjects - A radiologic study

G. O. Littlejohn; S. Hall

doi:10.1007/BF00541250

Diffuse idiopathic skeletal hyperostosis and new bone formation in male gouty subjects - A radiologic study

G. O. Littlejohn, S. Hall

Research output: Contribution to journal › Article › Research › peer-review

28 Citations (Scopus)

Abstract

Ninety-nine males with gout were identified and their radiographs examined for features of vertebral hyperostosis and entheseal changes (diffuse idiopathic skeletal hyperostosis, DISH). Of patients over the age of 45 years 43% fulfilled criteria for diagnosis of DISH. New bone formation in other regions of the skeleton was also common. The overhanging margin sign, seen in well developed tophi, was noted only in patients with prominent new bone formation elsewhere in their skeleton. Some of the radiologic manifestations of gout may be modified by a co-existent tendency, in these patients, to form new bone. It is suggested that a common metabolic factor, possibly hyperinsulinaemia, underlies the association of gout and hyperostosis.

Original language	English
Pages (from-to)	83-86
Number of pages	4
Journal	Rheumatology International
Volume	2
Issue number	2
DOIs	https://doi.org/10.1007/BF00541250
Publication status	Published - 1 Jun 1982

Keywords

Ankylosing hyperostosis
Diffuse idiopathic skeletal hyperostosis
Gout
New bone

Cite this

Littlejohn, G. O., & Hall, S. (1982). Diffuse idiopathic skeletal hyperostosis and new bone formation in male gouty subjects - A radiologic study. Rheumatology International, 2(2), 83-86. https://doi.org/10.1007/BF00541250

Littlejohn, G. O. ; Hall, S. / Diffuse idiopathic skeletal hyperostosis and new bone formation in male gouty subjects - A radiologic study. In: Rheumatology International. 1982 ; Vol. 2, No. 2. pp. 83-86.

@article{2010880a8b1c4232a8c59565bbf221ad,

title = "Diffuse idiopathic skeletal hyperostosis and new bone formation in male gouty subjects - A radiologic study",

abstract = "Ninety-nine males with gout were identified and their radiographs examined for features of vertebral hyperostosis and entheseal changes (diffuse idiopathic skeletal hyperostosis, DISH). Of patients over the age of 45 years 43{\%} fulfilled criteria for diagnosis of DISH. New bone formation in other regions of the skeleton was also common. The overhanging margin sign, seen in well developed tophi, was noted only in patients with prominent new bone formation elsewhere in their skeleton. Some of the radiologic manifestations of gout may be modified by a co-existent tendency, in these patients, to form new bone. It is suggested that a common metabolic factor, possibly hyperinsulinaemia, underlies the association of gout and hyperostosis.",

keywords = "Ankylosing hyperostosis, Diffuse idiopathic skeletal hyperostosis, Gout, New bone",

author = "Littlejohn, {G. O.} and S. Hall",

year = "1982",

month = "6",

day = "1",

doi = "10.1007/BF00541250",

language = "English",

volume = "2",

pages = "83--86",

journal = "Rheumatology International",

issn = "0172-8172",

publisher = "Springer-Verlag London Ltd.",

number = "2",

}

Littlejohn, GO & Hall, S 1982, 'Diffuse idiopathic skeletal hyperostosis and new bone formation in male gouty subjects - A radiologic study', Rheumatology International, vol. 2, no. 2, pp. 83-86. https://doi.org/10.1007/BF00541250

Diffuse idiopathic skeletal hyperostosis and new bone formation in male gouty subjects - A radiologic study. / Littlejohn, G. O.; Hall, S.

In: Rheumatology International, Vol. 2, No. 2, 01.06.1982, p. 83-86.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Diffuse idiopathic skeletal hyperostosis and new bone formation in male gouty subjects - A radiologic study

AU - Littlejohn, G. O.

AU - Hall, S.

PY - 1982/6/1

Y1 - 1982/6/1

N2 - Ninety-nine males with gout were identified and their radiographs examined for features of vertebral hyperostosis and entheseal changes (diffuse idiopathic skeletal hyperostosis, DISH). Of patients over the age of 45 years 43% fulfilled criteria for diagnosis of DISH. New bone formation in other regions of the skeleton was also common. The overhanging margin sign, seen in well developed tophi, was noted only in patients with prominent new bone formation elsewhere in their skeleton. Some of the radiologic manifestations of gout may be modified by a co-existent tendency, in these patients, to form new bone. It is suggested that a common metabolic factor, possibly hyperinsulinaemia, underlies the association of gout and hyperostosis.

AB - Ninety-nine males with gout were identified and their radiographs examined for features of vertebral hyperostosis and entheseal changes (diffuse idiopathic skeletal hyperostosis, DISH). Of patients over the age of 45 years 43% fulfilled criteria for diagnosis of DISH. New bone formation in other regions of the skeleton was also common. The overhanging margin sign, seen in well developed tophi, was noted only in patients with prominent new bone formation elsewhere in their skeleton. Some of the radiologic manifestations of gout may be modified by a co-existent tendency, in these patients, to form new bone. It is suggested that a common metabolic factor, possibly hyperinsulinaemia, underlies the association of gout and hyperostosis.

KW - Ankylosing hyperostosis

KW - Diffuse idiopathic skeletal hyperostosis

KW - Gout

KW - New bone

UR - http://www.scopus.com/inward/record.url?scp=0020323212&partnerID=8YFLogxK

U2 - 10.1007/BF00541250

DO - 10.1007/BF00541250

M3 - Article

VL - 2

SP - 83

EP - 86

JO - Rheumatology International