Differentiating Right-and Left-Sided Outflow Tract Ventricular Arrhythmias: Classical ECG Signatures and Prediction Algorithms

Robert D. Anderson, Saurabh Kumar, Ramanathan Parameswaran, Geoffrey Wong, Aleksandr Voskoboinik, Hariharan Sugumar, Troy Watts, Paul B. Sparks, Joseph B. Morton, Alex McLellan, Peter M. Kistler, Jonathan Kalman, Geoffrey Lee

Research output: Contribution to journalReview ArticleResearchpeer-review

56 Citations (Scopus)


Idiopathic ventricular arrhythmias commonly originate from the right ventricular and left ventricular outflow tracts (OTs). Advances in real-time imaging have refined our understanding of the intimate anatomic structures implicated in the genesis of OT arrhythmias, making catheter ablation for arrhythmias beyond the right ventricular OT a feasible option for cure-indeed ablation is now a class I indication in recent guidelines. The surface 12-lead ECG is routinely used to localize the anatomic site of origin before catheter ablation. However, the intimate and complex anatomy of the OT limits predictive value ECG criteria alone for localization for these arrhythmias. Multiple ECG algorithms have been developed to assist preprocedural localization, and hence predict safety and efficacy for catheter ablation of OT ventricular arrhythmias. This review will summarize all of the published 12-lead ECG algorithms used to guide localization of OT ventricular arrhythmias.

Original languageEnglish
Article numbere007392
Number of pages15
JournalCirculation: Arrhythmia and Electrophysiology
Issue number6
Publication statusPublished - 1 Jun 2019
Externally publishedYes


  • algorithms
  • cardiac arrhythmia
  • catheter ablation
  • electrocardiography

Cite this