Differential responses to blood pressure and oxidative stress in streptozotocin-induced diabetic Wistar-Kyoto rats and spontaneously hypertensive rats: Effects of antioxidant (honey) treatment

Omotayo Erejuwa; Siti Sulaiman; Mohd Suhaimi Ab Wahab; K Sirajudeen; Md Md Salleh; Sunil Gurtu

doi:10.3390/ijms12031888

Differential responses to blood pressure and oxidative stress in streptozotocin-induced diabetic Wistar-Kyoto rats and spontaneously hypertensive rats: Effects of antioxidant (honey) treatment

Omotayo Erejuwa, Siti Sulaiman, Mohd Suhaimi Ab Wahab, K Sirajudeen, Md Md Salleh, Sunil Gurtu

Research output: Contribution to journal › Article › Research › peer-review

37 Citations (Scopus)

Abstract

Oxidative stress is implicated in the pathogenesis and/or complications of hypertension and/or diabetes mellitus. A combination of these disorders increases the risk of developing cardiovascular events. This study investigated the effects of streptozotocin (60 mg/kg; ip)-induced diabetes on blood pressure, oxidative stress and effects of honey on these parameters in the kidneys of streptozotocin-induced diabetic Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR).

Original language	English
Pages (from-to)	1888 - 1907
Number of pages	20
Journal	International Journal of Molecular Sciences
Volume	12
Issue number	3
DOIs	https://doi.org/10.3390/ijms12031888
Publication status	Published - 2011

Access to Document

10.3390/ijms12031888

RM sElocation

Cite this

Erejuwa, O., Sulaiman, S., Ab Wahab, M. S., Sirajudeen, K., Md Salleh, M., & Gurtu, S. (2011). Differential responses to blood pressure and oxidative stress in streptozotocin-induced diabetic Wistar-Kyoto rats and spontaneously hypertensive rats: Effects of antioxidant (honey) treatment. International Journal of Molecular Sciences, 12(3), 1888 - 1907. https://doi.org/10.3390/ijms12031888

Erejuwa, Omotayo ; Sulaiman, Siti ; Ab Wahab, Mohd Suhaimi ; Sirajudeen, K ; Md Salleh, Md ; Gurtu, Sunil. / Differential responses to blood pressure and oxidative stress in streptozotocin-induced diabetic Wistar-Kyoto rats and spontaneously hypertensive rats: Effects of antioxidant (honey) treatment. In: International Journal of Molecular Sciences. 2011 ; Vol. 12, No. 3. pp. 1888 - 1907.

@article{91675c6bf3724422b4dcd5d84c864bce,

title = "Differential responses to blood pressure and oxidative stress in streptozotocin-induced diabetic Wistar-Kyoto rats and spontaneously hypertensive rats: Effects of antioxidant (honey) treatment",

abstract = "Oxidative stress is implicated in the pathogenesis and/or complications of hypertension and/or diabetes mellitus. A combination of these disorders increases the risk of developing cardiovascular events. This study investigated the effects of streptozotocin (60 mg/kg; ip)-induced diabetes on blood pressure, oxidative stress and effects of honey on these parameters in the kidneys of streptozotocin-induced diabetic Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR).",

author = "Omotayo Erejuwa and Siti Sulaiman and {Ab Wahab}, {Mohd Suhaimi} and K Sirajudeen and {Md Salleh}, Md and Sunil Gurtu",

year = "2011",

doi = "10.3390/ijms12031888",

language = "English",

volume = "12",

pages = "1888 -- 1907",

journal = "International Journal of Molecular Sciences",

issn = "1422-0067",

publisher = "MDPI AG",

number = "3",

}

Erejuwa, O, Sulaiman, S, Ab Wahab, MS, Sirajudeen, K, Md Salleh, M & Gurtu, S 2011, 'Differential responses to blood pressure and oxidative stress in streptozotocin-induced diabetic Wistar-Kyoto rats and spontaneously hypertensive rats: Effects of antioxidant (honey) treatment', International Journal of Molecular Sciences, vol. 12, no. 3, pp. 1888 - 1907. https://doi.org/10.3390/ijms12031888

Differential responses to blood pressure and oxidative stress in streptozotocin-induced diabetic Wistar-Kyoto rats and spontaneously hypertensive rats: Effects of antioxidant (honey) treatment. / Erejuwa, Omotayo; Sulaiman, Siti; Ab Wahab, Mohd Suhaimi; Sirajudeen, K; Md Salleh, Md; Gurtu, Sunil.

In: International Journal of Molecular Sciences, Vol. 12, No. 3, 2011, p. 1888 - 1907.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Differential responses to blood pressure and oxidative stress in streptozotocin-induced diabetic Wistar-Kyoto rats and spontaneously hypertensive rats: Effects of antioxidant (honey) treatment

AU - Erejuwa, Omotayo

AU - Sulaiman, Siti

AU - Ab Wahab, Mohd Suhaimi

AU - Sirajudeen, K

AU - Md Salleh, Md

AU - Gurtu, Sunil

PY - 2011

Y1 - 2011

N2 - Oxidative stress is implicated in the pathogenesis and/or complications of hypertension and/or diabetes mellitus. A combination of these disorders increases the risk of developing cardiovascular events. This study investigated the effects of streptozotocin (60 mg/kg; ip)-induced diabetes on blood pressure, oxidative stress and effects of honey on these parameters in the kidneys of streptozotocin-induced diabetic Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR).

AB - Oxidative stress is implicated in the pathogenesis and/or complications of hypertension and/or diabetes mellitus. A combination of these disorders increases the risk of developing cardiovascular events. This study investigated the effects of streptozotocin (60 mg/kg; ip)-induced diabetes on blood pressure, oxidative stress and effects of honey on these parameters in the kidneys of streptozotocin-induced diabetic Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR).

UR - http://www.mdpi.com/1422-0067/12/3/1888/

U2 - 10.3390/ijms12031888

DO - 10.3390/ijms12031888

M3 - Article

VL - 12

SP - 1888

EP - 1907

JO - International Journal of Molecular Sciences

JF - International Journal of Molecular Sciences

SN - 1422-0067

IS - 3

ER -

Erejuwa O, Sulaiman S, Ab Wahab MS, Sirajudeen K, Md Salleh M, Gurtu S. Differential responses to blood pressure and oxidative stress in streptozotocin-induced diabetic Wistar-Kyoto rats and spontaneously hypertensive rats: Effects of antioxidant (honey) treatment. International Journal of Molecular Sciences. 2011;12(3):1888 - 1907. https://doi.org/10.3390/ijms12031888