TY - JOUR
T1 - Differential responses to blood pressure and oxidative stress in streptozotocin-induced diabetic Wistar-Kyoto rats and spontaneously hypertensive rats: Effects of antioxidant (honey) treatment
AU - Erejuwa, Omotayo
AU - Sulaiman, Siti
AU - Ab Wahab, Mohd Suhaimi
AU - Sirajudeen, K
AU - Md Salleh, Md
AU - Gurtu, Sunil
PY - 2011
Y1 - 2011
N2 - Oxidative stress is implicated in the pathogenesis and/or complications of hypertension and/or diabetes mellitus. A combination of these disorders increases the risk of developing cardiovascular events. This study investigated the effects of streptozotocin (60 mg/kg; ip)-induced diabetes on blood pressure, oxidative stress and effects of honey on these parameters in the kidneys of streptozotocin-induced diabetic Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR).
AB - Oxidative stress is implicated in the pathogenesis and/or complications of hypertension and/or diabetes mellitus. A combination of these disorders increases the risk of developing cardiovascular events. This study investigated the effects of streptozotocin (60 mg/kg; ip)-induced diabetes on blood pressure, oxidative stress and effects of honey on these parameters in the kidneys of streptozotocin-induced diabetic Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR).
UR - http://www.mdpi.com/1422-0067/12/3/1888/
U2 - 10.3390/ijms12031888
DO - 10.3390/ijms12031888
M3 - Article
VL - 12
SP - 1888
EP - 1907
JO - International Journal of Molecular Sciences
JF - International Journal of Molecular Sciences
SN - 1422-0067
IS - 3
ER -