The purpose of study was to compare the effect of primary motor cortex (M1) and cerebellar anodal transcranial direct current stimulation (a-tDCS) on online and offline motor learning in healthy individuals. Fifty-nine healthy volunteers were randomly divided into three groups (n =20 in two experimental groups and n =19 in sham-control group). One experimental group received M1a-tDCSand another received cerebellar a-tDCS. The main outcome measure were response time (RT) and number of errors during serial response time test (SRTT) which were assessed prior, 35min and 48h after the interventions. Reduction of response time (RT) and error numbers at last block of the test compared to the first block was considered online learning. Comparison of assessments during retention tests was considered as short-term and long-term offline learning. Online RT reduction was not different among groups (P >0.05), while online error reduction was significantly greater in cerebellar a-tDCS than sham-control group (P 1 and cerebellar a-tDCS can be used as a boosting technique for improvement of offline motor learning in healthy individuals.
- Motor learning
- Primary motor cortex
- Serial reaction time test
- Transcranial direct current stimulation