Different surface charge of colistin-susceptible and -resistant acinetobacter baumannii cells measured with zeta potential as a function of growth phase and colistin treatment

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Abstract

electrostatic forces mediate the initial interaction between cationic colistin and Gram-negative bacterial cells. Lipopolysaccharide (LPS) loss mediates colistin resistance in some A. baumannii strains. Our aim was to determine the surface charge of colistin-susceptible and -resistant A. baumannii as a function of growth phase and in response to polymyxin treatment.
Original languageEnglish
Pages (from-to)126 - 133
Number of pages8
JournalJournal of Antimicrobial Chemotherapy
Volume66
Issue number1
DOIs
Publication statusPublished - 2011

Cite this

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title = "Different surface charge of colistin-susceptible and -resistant acinetobacter baumannii cells measured with zeta potential as a function of growth phase and colistin treatment",
abstract = "electrostatic forces mediate the initial interaction between cationic colistin and Gram-negative bacterial cells. Lipopolysaccharide (LPS) loss mediates colistin resistance in some A. baumannii strains. Our aim was to determine the surface charge of colistin-susceptible and -resistant A. baumannii as a function of growth phase and in response to polymyxin treatment.",
author = "Rachel Soon and Roger Nation and Stewart Cockram and Jennifer Moffatt and Marina Harper and Ben Adler and John Boyce and Ian Larson and Jian Li",
year = "2011",
doi = "10.1093/jac/dkq422",
language = "English",
volume = "66",
pages = "126 -- 133",
journal = "Journal of Antimicrobial Chemotherapy",
issn = "0305-7453",
publisher = "Oxford University Press",
number = "1",

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T1 - Different surface charge of colistin-susceptible and -resistant acinetobacter baumannii cells measured with zeta potential as a function of growth phase and colistin treatment

AU - Soon, Rachel

AU - Nation, Roger

AU - Cockram, Stewart

AU - Moffatt, Jennifer

AU - Harper, Marina

AU - Adler, Ben

AU - Boyce, John

AU - Larson, Ian

AU - Li, Jian

PY - 2011

Y1 - 2011

N2 - electrostatic forces mediate the initial interaction between cationic colistin and Gram-negative bacterial cells. Lipopolysaccharide (LPS) loss mediates colistin resistance in some A. baumannii strains. Our aim was to determine the surface charge of colistin-susceptible and -resistant A. baumannii as a function of growth phase and in response to polymyxin treatment.

AB - electrostatic forces mediate the initial interaction between cationic colistin and Gram-negative bacterial cells. Lipopolysaccharide (LPS) loss mediates colistin resistance in some A. baumannii strains. Our aim was to determine the surface charge of colistin-susceptible and -resistant A. baumannii as a function of growth phase and in response to polymyxin treatment.

U2 - 10.1093/jac/dkq422

DO - 10.1093/jac/dkq422

M3 - Article

C2 - 21081544

VL - 66

SP - 126

EP - 133

JO - Journal of Antimicrobial Chemotherapy

JF - Journal of Antimicrobial Chemotherapy

SN - 0305-7453

IS - 1

ER -