Different surface charge of colistin-susceptible and -resistant acinetobacter baumannii cells measured with zeta potential as a function of growth phase and colistin treatment

Rachel Soon; Roger Nation; Stewart Cockram; Jennifer Moffatt; Marina Harper; Ben Adler; John Boyce; Ian Larson; Jian Li

doi:10.1093/jac/dkq422

Different surface charge of colistin-susceptible and -resistant acinetobacter baumannii cells measured with zeta potential as a function of growth phase and colistin treatment

Rachel Soon, Roger Nation, Stewart Cockram, Jennifer Moffatt, Marina Harper, Ben Adler, John Boyce, Ian Larson, Jian Li

Research output: Contribution to journal › Article › Research › peer-review

57 Citations (Scopus)

Abstract

electrostatic forces mediate the initial interaction between cationic colistin and Gram-negative bacterial cells. Lipopolysaccharide (LPS) loss mediates colistin resistance in some A. baumannii strains. Our aim was to determine the surface charge of colistin-susceptible and -resistant A. baumannii as a function of growth phase and in response to polymyxin treatment.

Original language	English
Pages (from-to)	126 - 133
Number of pages	8
Journal	Journal of Antimicrobial Chemotherapy
Volume	66
Issue number	1
DOIs	https://doi.org/10.1093/jac/dkq422
Publication status	Published - 2011

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10.1093/jac/dkq422

Cite this

Soon, R., Nation, R., Cockram, S., Moffatt, J., Harper, M., Adler, B., Boyce, J., Larson, I., & Li, J. (2011). Different surface charge of colistin-susceptible and -resistant acinetobacter baumannii cells measured with zeta potential as a function of growth phase and colistin treatment. Journal of Antimicrobial Chemotherapy, 66(1), 126 - 133. https://doi.org/10.1093/jac/dkq422

Soon, Rachel ; Nation, Roger ; Cockram, Stewart ; Moffatt, Jennifer ; Harper, Marina ; Adler, Ben ; Boyce, John ; Larson, Ian ; Li, Jian. / Different surface charge of colistin-susceptible and -resistant acinetobacter baumannii cells measured with zeta potential as a function of growth phase and colistin treatment. In: Journal of Antimicrobial Chemotherapy. 2011 ; Vol. 66, No. 1. pp. 126 - 133.

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title = "Different surface charge of colistin-susceptible and -resistant acinetobacter baumannii cells measured with zeta potential as a function of growth phase and colistin treatment",

abstract = "electrostatic forces mediate the initial interaction between cationic colistin and Gram-negative bacterial cells. Lipopolysaccharide (LPS) loss mediates colistin resistance in some A. baumannii strains. Our aim was to determine the surface charge of colistin-susceptible and -resistant A. baumannii as a function of growth phase and in response to polymyxin treatment.",

author = "Rachel Soon and Roger Nation and Stewart Cockram and Jennifer Moffatt and Marina Harper and Ben Adler and John Boyce and Ian Larson and Jian Li",

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language = "English",

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Soon, R, Nation, R, Cockram, S, Moffatt, J, Harper, M , Adler, B , Boyce, J , Larson, I & Li, J 2011, 'Different surface charge of colistin-susceptible and -resistant acinetobacter baumannii cells measured with zeta potential as a function of growth phase and colistin treatment', Journal of Antimicrobial Chemotherapy, vol. 66, no. 1, pp. 126 - 133. https://doi.org/10.1093/jac/dkq422

Different surface charge of colistin-susceptible and -resistant acinetobacter baumannii cells measured with zeta potential as a function of growth phase and colistin treatment. / Soon, Rachel; Nation, Roger; Cockram, Stewart; Moffatt, Jennifer; Harper, Marina ; Adler, Ben ; Boyce, John ; Larson, Ian ; Li, Jian.

In: Journal of Antimicrobial Chemotherapy, Vol. 66, No. 1, 2011, p. 126 - 133.

Research output: Contribution to journal › Article › Research › peer-review

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AU - Soon, Rachel

AU - Nation, Roger

AU - Cockram, Stewart

AU - Moffatt, Jennifer

AU - Harper, Marina

AU - Adler, Ben

AU - Boyce, John

AU - Larson, Ian

AU - Li, Jian

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AB - electrostatic forces mediate the initial interaction between cationic colistin and Gram-negative bacterial cells. Lipopolysaccharide (LPS) loss mediates colistin resistance in some A. baumannii strains. Our aim was to determine the surface charge of colistin-susceptible and -resistant A. baumannii as a function of growth phase and in response to polymyxin treatment.

U2 - 10.1093/jac/dkq422

DO - 10.1093/jac/dkq422

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JO - Journal of Antimicrobial Chemotherapy

JF - Journal of Antimicrobial Chemotherapy

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