DHEA replacement for postmenopausal women

Susan Davis, Mary Panjari, Frank Stanczyk

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84 Citations (Scopus)

Abstract

Context It has been proposed that because dehydroepiandrosterone (DHEA) and its sulfate, DHEAS, are important precursors for estrogen and androgen production, treatment with DHEA is a physiologically based strategy for the alleviation of hormone deficiency symptoms in postmenopausal women. We have summarized the physiology of DHEA in women and reviewed the findings from randomized controlled trials (RCT) of the effects of DHEA therapy in postmenopausal women with normal adrenal function.
Original languageEnglish
Pages (from-to)1642 - 1653
Number of pages12
JournalJournal of Clinical Endocrinology and Metabolism
Volume96
Issue number6
DOIs
Publication statusPublished - 2011

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