Dexmedetomidine vs. haloperidol in delirious, agitated, intubated patients: a randomised open-label trial

Michael C Reade, Kim O'Sullivan, Samantha Bates, Donna Goldsmith, William R S T J Ainslie, Rinaldo Bellomo

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Abstract

Agitated delirium is common in patients undergoing mechanical ventilation, and is often treated with haloperidol despite concerns about safety and efficacy. Use of conventional sedatives to control agitation can preclude extubation. Dexmedetomidine, a novel sedative and anxiolytic agent, may have particular utility in these patients. We sought to compare the efficacy of haloperidol and dexmedetomidine in facilitating extubation.
Original languageEnglish
Pages (from-to)1 - 10
Number of pages10
JournalCritical Care
Volume13
Issue number3 (Art.No.: R75)
DOIs
Publication statusPublished - 2009
Externally publishedYes

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