The effect of intramuscular dexamethasone administration in late pregnancy on the maternal peripheral white cell count was examined in 20 women. The mean total white cell count increased from a baseline of 11-3 × 109/L (SD 2-3) to 16-2 × 109/L (SD 4-6) on day 1, normalising thereafter. This 43% increase represented composite changes in the neutrophil and lymphocyte counts which, on average, increased by 62% and decreased by 22%, respectively. It is concluded that prenatal dexamethasone induces a significant neutrophilia on the first day following administration. This information may be helpful when monitoring for infection.
|Number of pages||3|
|Journal||British Journal of Obstetrics and Gynaecology|
|Publication status||Published - Jul 1997|