Development of the Kidney: Morphology and mechanisms

Ian M. Smyth; Luise A. Cullen-McEwen; Georgina Caruana; M. Jane Black; John F. Bertram

doi:10.1016/B978-0-323-35214-7.00099-8

Development of the Kidney: Morphology and mechanisms

Ian M. Smyth, Luise A. Cullen-McEwen, Georgina Caruana, M. Jane Black, John F. Bertram

Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review

9 Citations (Scopus)

Abstract

The development of the mammalian kidney has been extensively studied for the past 60 to 70 years, and our understanding of renal development and molecular regulation is perhaps better understood than that of any other organ. This chapter provides an overview of the development of the three mammalian excretory organs (pronephroi, mesonephroi, and metanephroi) but explores metanephric development in detail. The processes of ureteric budding, ureteric branching morphogenesis, and nephrogenesis are also described in detail, as is our current understanding of the nature and roles of renal progenitor cells. In addition, the roles of the renal stroma in kidney development are considered, and renal vascular development is described. Finally, the effects of preterm birth on kidney development are addressed.

Original language	English
Title of host publication	Fetal and Neonatal Physiology
Editors	Richard A. Polin, Steven H. Abman, David H. Rowitch, William E. Benitz, William W. Fox
Place of Publication	Philadelphia, PA
Publisher	Elsevier
Chapter	99
Pages	953-964.e4
Number of pages	16
Volume	2
Edition	5th
ISBN (Electronic)	9780323352147
ISBN (Print)	9780323352338
DOIs	https://doi.org/10.1016/B978-0-323-35214-7.00099-8
Publication status	Published - 2017

Access to Document

10.1016/B978-0-323-35214-7.00099-8

Cite this

@inbook{5e33d2aa6df640c6af39448fcd30219a,

title = "Development of the Kidney: Morphology and mechanisms",

abstract = "The development of the mammalian kidney has been extensively studied for the past 60 to 70 years, and our understanding of renal development and molecular regulation is perhaps better understood than that of any other organ. This chapter provides an overview of the development of the three mammalian excretory organs (pronephroi, mesonephroi, and metanephroi) but explores metanephric development in detail. The processes of ureteric budding, ureteric branching morphogenesis, and nephrogenesis are also described in detail, as is our current understanding of the nature and roles of renal progenitor cells. In addition, the roles of the renal stroma in kidney development are considered, and renal vascular development is described. Finally, the effects of preterm birth on kidney development are addressed.",

author = "Smyth, {Ian M.} and Cullen-McEwen, {Luise A.} and Georgina Caruana and Black, {M. Jane} and Bertram, {John F.}",

year = "2017",

doi = "10.1016/B978-0-323-35214-7.00099-8",

language = "English",

isbn = "9780323352338",

volume = "2",

pages = "953--964.e4",

editor = "Polin, {Richard A.} and Abman, {Steven H.} and Rowitch, {David H.} and Benitz, {William E.} and Fox, {William W.}",

booktitle = "Fetal and Neonatal Physiology",

publisher = "Elsevier",

address = "Netherlands",

edition = "5th",

}

Development of the Kidney: Morphology and mechanisms. / Smyth, Ian M.; Cullen-McEwen, Luise A.; Caruana, Georgina et al.
Fetal and Neonatal Physiology. ed. / Richard A. Polin; Steven H. Abman; David H. Rowitch; William E. Benitz; William W. Fox. Vol. 2 5th. ed. Philadelphia, PA: Elsevier, 2017. p. 953-964.e4.

Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review

TY - CHAP

T1 - Development of the Kidney

T2 - Morphology and mechanisms

AU - Smyth, Ian M.

AU - Cullen-McEwen, Luise A.

AU - Caruana, Georgina

AU - Black, M. Jane

AU - Bertram, John F.

PY - 2017

Y1 - 2017

N2 - The development of the mammalian kidney has been extensively studied for the past 60 to 70 years, and our understanding of renal development and molecular regulation is perhaps better understood than that of any other organ. This chapter provides an overview of the development of the three mammalian excretory organs (pronephroi, mesonephroi, and metanephroi) but explores metanephric development in detail. The processes of ureteric budding, ureteric branching morphogenesis, and nephrogenesis are also described in detail, as is our current understanding of the nature and roles of renal progenitor cells. In addition, the roles of the renal stroma in kidney development are considered, and renal vascular development is described. Finally, the effects of preterm birth on kidney development are addressed.

AB - The development of the mammalian kidney has been extensively studied for the past 60 to 70 years, and our understanding of renal development and molecular regulation is perhaps better understood than that of any other organ. This chapter provides an overview of the development of the three mammalian excretory organs (pronephroi, mesonephroi, and metanephroi) but explores metanephric development in detail. The processes of ureteric budding, ureteric branching morphogenesis, and nephrogenesis are also described in detail, as is our current understanding of the nature and roles of renal progenitor cells. In addition, the roles of the renal stroma in kidney development are considered, and renal vascular development is described. Finally, the effects of preterm birth on kidney development are addressed.

UR - http://www.scopus.com/inward/record.url?scp=85112246630&partnerID=8YFLogxK

U2 - 10.1016/B978-0-323-35214-7.00099-8

DO - 10.1016/B978-0-323-35214-7.00099-8

M3 - Chapter (Book)

AN - SCOPUS:85112246630

SN - 9780323352338

VL - 2

SP - 953-964.e4

BT - Fetal and Neonatal Physiology

A2 - Polin, Richard A.

A2 - Abman, Steven H.

A2 - Rowitch, David H.

A2 - Benitz, William E.

A2 - Fox, William W.

PB - Elsevier

CY - Philadelphia, PA

ER -

Development of the Kidney: Morphology and mechanisms

Abstract

Access to Document

Other files and links

Cite this