Abstract
OBJECTIVE:: A work function measure specific for persons with prodromal Huntington disease (HD) was created to assist with workplace accommodations. METHODS:: A self-report HD Work Function (HDWF) measure was developed from focus group and expert validation. RESULTS:: Pilot studies with 238 people with prodromal HD, and 185 companions; and 89 people without prodromal HD, and 70 companions indicate that HDWF has acceptable internal consistency (Cronbach α = 0.77), acceptable interrater reliability (r = 0.58), and acceptable convergent validity with selected items from the Endicott Work Productivity Scale (r = -0.56), Social Adjustment Scale-Self Report (r = -0.29), and Everyday Cognition (r = -0.70). The HDWF can distinguish between people with prodromal HD and people with an HD family history who do not have prodromal HD (P < 0.0001). CONCLUSIONS:: The HDWF is a brief self-assessment that may be used to monitor work function.
Original language | English |
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Pages (from-to) | 1300-1308 |
Number of pages | 9 |
Journal | Journal of Occupational and Environmental Medicine |
Volume | 54 |
Issue number | 10 |
DOIs | |
Publication status | Published - 1 Oct 2012 |
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In: Journal of Occupational and Environmental Medicine, Vol. 54, No. 10, 01.10.2012, p. 1300-1308.
Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Development of the Huntington disease work function scale
AU - Brossman, Bradley
AU - Williams, Janet
AU - Downing, Nancy
AU - Mills, James A.
AU - Paulsen, Jane S.
AU - Wassink, Thomas
AU - Cross, Stephen
AU - Kimble, Mycah
AU - Ryan, Patricia
AU - Wood, Jessica
AU - Epping, Eric A.
AU - Beglinger, Leigh J.
AU - Chiu, Edmond
AU - Yastrubetskaya, Olga
AU - Preston, Joy
AU - Goh, Anita
AU - Fonseka, Chathushka
AU - Antonopoulos, Stephanie
AU - Loi, Samantha
AU - Chua, Phyllis
AU - Komiti, Angela
AU - Raymond, Lynn
AU - Dar Santos, Rachelle
AU - Carter, Kimberley
AU - Decolongon, Joji
AU - Rosenblatt, Adam
AU - Ross, Christopher A.
AU - Shpritz, Barnett
AU - Yoritomo, Nadine
AU - Welsh, Claire
AU - Mallonee, William M.
AU - Suter, Greg
AU - Addison, Judy
AU - Samii, Ali
AU - Macaraeg, Alma
AU - Jones, Randi
AU - Wood-Siverio, Cathy
AU - Factor, Stewart A.
AU - Testa, Claudia
AU - Barker, Roger A.
AU - Mason, Sarah
AU - Goodman, Anna
AU - Dipietro, Anna
AU - McCusker, Elizabeth
AU - Griffith, Jane
AU - Loy, Clement
AU - Gunn, David
AU - Landwehrmeyer, Bernhard G.
AU - Orth, Michael
AU - Süβmuth, Sigurd
AU - Barth, Katrin
AU - Trautmann, Sonja
AU - Quaid, Kimberly
AU - Wesson, Melissa
AU - Wojcieszek, Joanne
AU - Guttman, Mark
AU - Sheinberg, Alanna
AU - Karmalkar, Irita
AU - Perlman, Susan
AU - Clemente, Brian
AU - Johnson, Arik
AU - Geschwind, Michael
AU - Gooblar, Jon
AU - Kang, Gail
AU - Warner, Tom
AU - Burrows, Maggie
AU - Novak, Marianne
AU - Andrews, Thomasin
AU - Rosser, Elisabeth
AU - Tabrizi, Sarah
AU - Rosser, Anne
AU - Price, Kathy
AU - Hunt, Sarah
AU - Marshall, Frederick
AU - Chesire, Amy
AU - Wodarski, Mary
AU - Hickey, Charlyne
AU - Suchowersky, Oksana
AU - Furtado, Sarah
AU - Klimek, Mary Lou
AU - Panegyres, Peter
AU - Lee, Joseph
AU - Andrew, Steve
AU - Perlmutter, Joel
AU - Barton, Stacey
AU - Schmidt, Amy
AU - Miedzybrodzka, Zosia
AU - Rae, Daniela
AU - D’alessandro, Mariella
AU - Craufurd, David
AU - Fullam, Ruth
AU - Bek, Judith
AU - Howard, Elizabeth
AU - Mazzoni, Pietro
AU - Marder, Karen
AU - Wasserman, Paula
AU - Kumar, Rajeev
AU - Erickson, Diane
AU - Wheelock, Vicki
AU - Tempkin, Terry
AU - Kjer, Lisa
AU - Baynes, Kathleen
AU - Jankovic, Joseph
AU - Hunter, Christine
AU - Ondo, William
AU - Martin, Wayne
AU - King, Pamela
AU - Wieler, Marguerite
AU - Sran, Satwinder
AU - Ahmed, Anwar
AU - Rao, Stephen
AU - Reece, Christine
AU - Zimbelman, Janice
AU - Bea, Alexandra
AU - Newman, Emily
AU - Bura, Alex
AU - Mourany, Lyla
AU - Schulz, Juliet
AU - Paulsen, Jane
AU - Johnson, Hans
AU - Smith, Megan
AU - Williams, Janet
AU - Long, Jeffrey D.
AU - Aylward, Elizabeth
AU - Biglan, Kevin
AU - Leavitt, Blair
AU - Macdonald, Marcy
AU - Nance, Martha
AU - Erwin, Cheryl
AU - Hayden, Michael
AU - Didonato, Stefano
AU - Evans, Ken
AU - Matson, Wayne
AU - Peterson, Asa
AU - Borowsky, Beth
AU - Juhl, Andrew
AU - Wang, Kai
AU - Weir, David
AU - Vonsattell, Jean Paul
AU - Moskowitz, Carol
AU - Leserman, Anne
AU - Schaul, Lynn
AU - Vik, Stacie
AU - Harrington, Deborah
AU - Castillo, Gabriel
AU - Morison, Jessica
AU - Reed, Jason
AU - Diaz, Michael
AU - Dobbins, Ian
AU - Hershey, Tamara
AU - Foster, Erin
AU - Moore, Deborah
AU - Westervelt, Holly
AU - Davis, Jennifer
AU - Tremont, Geoff
AU - Moser, David
AU - Rowe, Kelly
AU - Wenman, Gloria
AU - Theriault, Danielle
AU - Gehl, Carissa
AU - Matheson, Kirsty
AU - Siedlecki, Karen
AU - Van Walsem, Marleen
AU - Bonner, Susan
AU - Elias, Greg
AU - Gover, Mary
AU - Bernier, Rachel
AU - Faust, Melanie
AU - Borowski, Beth
AU - Carlozzi, Noelle
AU - Duff, Kevin
AU - Georgiou-Karistianis, Nellie
AU - Stout, Julie
AU - Lange, Herwig
AU - Papp, Kate
AU - Ro, Eunyoe
AU - Clark, Lee Anna
AU - Laing, Joan
AU - Rees, Kristine
AU - Harreld, Michelle
AU - Ready, Rebecca
AU - Vaccarino, Anthony
AU - Farias, Sarah
AU - Gusella, Jim
AU - Myers, Rick
AU - Juhl, Andrew
AU - Pierson, Ron
AU - Jones, Kathy
AU - Marietta, Jacquie
AU - McDowell, William
AU - Harris, Greg
AU - Kim, Eun Young
AU - Ashburner, John
AU - Potkin, Steve
AU - Toga, Arthur
AU - Axelson, Eric
AU - Miller, Michael
AU - Reading, Sarah
AU - Beg, Mirza Faisal
AU - Magnotta, Vincent A.
AU - Helmer, Karl
AU - Lim, Kelvin
AU - Lowe, Mark
AU - Mori, Sasumu
AU - Song, Allen
AU - Turner, Jessica
AU - Rao, Steve
AU - Beall, Erik
AU - Koenig, Katherine
AU - Phillips, Michael
AU - Bryant, April
AU - Corey-Bloom, Jody
AU - Geschwind, Michael
AU - Reilmann, Ralf
AU - Unds, Zerka
AU - Fiedorowicz, Jess
AU - Robinson, Robert
AU - Ruggle, Adam
AU - Liu, Dawei
AU - Moser, David
AU - Anderson, Karen
AU - Groves, Mark
AU - Rickards, Hugh
AU - van Duijn, Eric
AU - Kim, Ji In
AU - Harrison, Blair
AU - Zhang, Ying
AU - Lu, Wenjing
AU - Lourens, Spencer
AU - Doucette, Nicholas
AU - Thumma, Kelli
AU - Waterman, Elijah
AU - Hinkel, Jeremy
AU - Hughes, Lisa
AU - Connell, R. J.
AU - Pease, Karen
AU - Rogers, Ben
AU - Smith, Jim
AU - Wu, Shuhua
AU - Zschiegner, Roland
AU - Carney, Erin
AU - McKirgan, Bill
AU - Scully, Mark
AU - Wyse, Ryan
AU - Bockholt, Jeremy
AU - Werling-Witkoske, Chris
AU - Ennis, Greg
AU - Anderson, Karla
AU - Rapp, Jennifer
AU - Thompson, Sean
AU - the PREDICT-HD Investigators and Coordinators of the Huntington Study Group
PY - 2012/10/1
Y1 - 2012/10/1
N2 - OBJECTIVE:: A work function measure specific for persons with prodromal Huntington disease (HD) was created to assist with workplace accommodations. METHODS:: A self-report HD Work Function (HDWF) measure was developed from focus group and expert validation. RESULTS:: Pilot studies with 238 people with prodromal HD, and 185 companions; and 89 people without prodromal HD, and 70 companions indicate that HDWF has acceptable internal consistency (Cronbach α = 0.77), acceptable interrater reliability (r = 0.58), and acceptable convergent validity with selected items from the Endicott Work Productivity Scale (r = -0.56), Social Adjustment Scale-Self Report (r = -0.29), and Everyday Cognition (r = -0.70). The HDWF can distinguish between people with prodromal HD and people with an HD family history who do not have prodromal HD (P < 0.0001). CONCLUSIONS:: The HDWF is a brief self-assessment that may be used to monitor work function.
AB - OBJECTIVE:: A work function measure specific for persons with prodromal Huntington disease (HD) was created to assist with workplace accommodations. METHODS:: A self-report HD Work Function (HDWF) measure was developed from focus group and expert validation. RESULTS:: Pilot studies with 238 people with prodromal HD, and 185 companions; and 89 people without prodromal HD, and 70 companions indicate that HDWF has acceptable internal consistency (Cronbach α = 0.77), acceptable interrater reliability (r = 0.58), and acceptable convergent validity with selected items from the Endicott Work Productivity Scale (r = -0.56), Social Adjustment Scale-Self Report (r = -0.29), and Everyday Cognition (r = -0.70). The HDWF can distinguish between people with prodromal HD and people with an HD family history who do not have prodromal HD (P < 0.0001). CONCLUSIONS:: The HDWF is a brief self-assessment that may be used to monitor work function.
UR - http://www.scopus.com/inward/record.url?scp=84867577975&partnerID=8YFLogxK
U2 - 10.1097/JOM.0b013e31825f30ab
DO - 10.1097/JOM.0b013e31825f30ab
M3 - Article
C2 - 22995807
AN - SCOPUS:84867577975
SN - 1076-2752
VL - 54
SP - 1300
EP - 1308
JO - Journal of Occupational and Environmental Medicine
JF - Journal of Occupational and Environmental Medicine
IS - 10
ER -