Determination of receptor binding kinetics of M1 muscarinic acetylcholine receptor (M1 mAChR) antagonists using whole cell binding

Darren Riddy; Arthur Christopoulos; Christopher Langmead

Determination of receptor binding kinetics of M1 muscarinic acetylcholine receptor (M1 mAChR) antagonists using whole cell binding

Drug Discovery Biology

Research output: Contribution to conference › Poster › peer-review

Abstract

The characterization of receptor binding kinetics of preclinical drug candidates is now becoming more readily appreciated as a key addition to the discovery process. Benefits of studying kinetics include increased understanding of prolonged duration of action, ability to differentiate between different pre-clinical candidates and in the understanding of differential in vivo efficacies.

Original language	English
Number of pages	1
Publication status	Published - 2014
Event	ASCEPT-MPGPCR 2014 - Melbourne Convention and Exhibition Centre, Melbourne, Australia Duration: 7 Dec 2014 → 11 Dec 2014 https://www.asceptasm.com/2014-annual-scientific-meeting/program-keynote-speakers/

Conference

Conference	ASCEPT-MPGPCR 2014
Abbreviated title	ASCEPT-MPGPCR
Country/Territory	Australia
City	Melbourne
Period	7/12/14 → 11/12/14
Internet address	https://www.asceptasm.com/2014-annual-scientific-meeting/program-keynote-speakers/

Cite this

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title = "Determination of receptor binding kinetics of M1 muscarinic acetylcholine receptor (M1 mAChR) antagonists using whole cell binding",

abstract = "The characterization of receptor binding kinetics of preclinical drug candidates is now becoming more readily appreciated as a key addition to the discovery process. Benefits of studying kinetics include increased understanding of prolonged duration of action, ability to differentiate between different pre-clinical candidates and in the understanding of differential in vivo efficacies.",

author = "Darren Riddy and Arthur Christopoulos and Christopher Langmead",

year = "2014",

language = "English",

note = "ASCEPT-MPGPCR 2014, ASCEPT-MPGPCR ; Conference date: 07-12-2014 Through 11-12-2014",

url = "https://www.asceptasm.com/2014-annual-scientific-meeting/program-keynote-speakers/",

}

TY - CONF

T1 - Determination of receptor binding kinetics of M1 muscarinic acetylcholine receptor (M1 mAChR) antagonists using whole cell binding

AU - Riddy, Darren

AU - Christopoulos, Arthur

AU - Langmead, Christopher

PY - 2014

Y1 - 2014

N2 - The characterization of receptor binding kinetics of preclinical drug candidates is now becoming more readily appreciated as a key addition to the discovery process. Benefits of studying kinetics include increased understanding of prolonged duration of action, ability to differentiate between different pre-clinical candidates and in the understanding of differential in vivo efficacies.

AB - The characterization of receptor binding kinetics of preclinical drug candidates is now becoming more readily appreciated as a key addition to the discovery process. Benefits of studying kinetics include increased understanding of prolonged duration of action, ability to differentiate between different pre-clinical candidates and in the understanding of differential in vivo efficacies.

M3 - Poster

T2 - ASCEPT-MPGPCR 2014

Y2 - 7 December 2014 through 11 December 2014

ER -