The characterization of receptor binding kinetics of preclinical drug candidates is now becoming more readily appreciated as a key addition to the discovery process. Benefits of studying kinetics include increased understanding of prolonged duration of action, ability to differentiate between different pre-clinical candidates and in the understanding of differential in vivo efficacies.
|Number of pages||1|
|Publication status||Published - 2014|
|Event||ASCEPT-MPGPCR 2014 - Melbourne Convention and Exhibition Centre, Melbourne, Australia|
Duration: 7 Dec 2014 → 11 Dec 2014
|Period||7/12/14 → 11/12/14|
Riddy, D., Christopoulos, A., & Langmead, C. (2014). Determination of receptor binding kinetics of M1 muscarinic acetylcholine receptor (M1 mAChR) antagonists using whole cell binding. Poster session presented at ASCEPT-MPGPCR 2014, Melbourne, Australia.