Detection of mcr-1-Carrying Escherichia coli Causing Bloodstream Infection in a New York City Hospital: Avian Origins, Human Concerns?

Nenad Macesic, Daniel Green, Zheng Wang, Sean B. Sullivan, Kevin Shim, Sarah Park, Susan Whittier, E. Yoko Furuya, Angela Gomez-Simmonds, Anne Catrin Uhlemanna

Research output: Contribution to journalArticleResearch

Abstract

The spread of mcr-1 in the United States remains poorly defined. mcr-1-producing Escherichia coli that also carried blaSHV-12 was detected in a hospitalized patient. No additional cases were identified during screening of 801 Gram-negative isolates. Genomic sequencing identified an IncX4 mcr-1- harboring plasmid and ST117 clonal background associated with avian pathogenic E coli.
Original languageEnglish
Article numberofx115
Number of pages4
JournalOpen Forum Infectious Diseases
Volume4
Issue number3
DOIs
Publication statusPublished - 20 May 2017
Externally publishedYes

Keywords

  • IncX4 plasmid
  • avian pathogenic E coli
  • colistin
  • mcr-1
  • polymyxin B

Cite this

Macesic, N., Green, D., Wang, Z., Sullivan, S. B., Shim, K., Park, S., Whittier, S., Furuya, E. Y., Gomez-Simmonds, A., & Uhlemanna, A. C. (2017). Detection of mcr-1-Carrying Escherichia coli Causing Bloodstream Infection in a New York City Hospital: Avian Origins, Human Concerns? Open Forum Infectious Diseases, 4(3), [ofx115]. https://doi.org/10.1093/ofid/ofx115