Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: A cause for hope?

Aeron Hurt, Naomi Komadina, Yi Mo Deng, Matthew Kaye, Sheena Sullivan, Kanta Subbarao, Ian Barr

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Abstract

For over a decade virtually all A(H3N2) influenza viruses have been resistant to the adamantane class of antivirals. However, during the 2017 influenza season in Australia, 15/461 (3.3%) adamantane-sensitive A(H3N2) viruses encoding serine at residue 31 of the M2 protein were detected, more than the total number identified globally during the last 6 years. A return to wide circulation of adamantane-sensitive A(H3N2) viruses would revive the option of using these drugs for treatment and prophylaxis.

Original languageEnglish
Article number17-00731
Number of pages8
JournalEurosurveillance
Volume22
Issue number47
DOIs
Publication statusPublished - 23 Nov 2017
Externally publishedYes

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