Design, synthesis and evaluation of novel 2-phenyl-3-(1H-pyrazol-4-yl)pyridine positive allosteric modulators for the M₄ mAChR

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  Discovering novel allosteric probes of muscarinic acetylcholine receptors

  Valant, C. (Primary Chief Investigator (PCI)), Scammells, P. (Chief Investigator (CI)) & Christopoulos, A. (Chief Investigator (CI))

  3/06/19 → 31/12/22

  Project: Research

• Translating membrane proteins into therapeutics; from bedside to bench

  Sexton, P. (Primary Chief Investigator (PCI)), Christopoulos, A. (Chief Investigator (CI)), Pantelis, C. (Chief Investigator (CI)) & Parton, R. G. (Chief Investigator (CI))

  1/01/19 → 31/12/23

  Project: Research

• Molecular insight into allosteric modulation of G protein-coupled receptors

  Thal, D. (Primary Chief Investigator (PCI))

  ARC - Australian Research Council

  1/01/17 → 31/12/19

  Project: Research

• Allosteric and Bitopic Ligands Acting at G Protein-Coupled Receptors

  Scammells, P. (Primary Chief Investigator (PCI)) & Christopoulos, A. (Chief Investigator (CI))

  ARC - Australian Research Council, Monash University

  1/01/16 → 30/06/19

  Project: Research