Design of Stimuli-Responsive Peptides and Proteins

Yang Li; Guangze Yang; Lukas Gerstweiler; San H. Thang; Chun Xia Zhao

doi:10.1002/adfm.202210387

Design of Stimuli-Responsive Peptides and Proteins

Yang Li, Guangze Yang, Lukas Gerstweiler, San H. Thang, Chun Xia Zhao

School of Chemistry

Research output: Contribution to journal › Review Article › Research › peer-review

24 Citations (Scopus)

Abstract

Stimuli-responsive peptides and proteins are an exciting class of smart biomaterials for various applications and have received significant attention over the past decades. A wide variety of stimuli such as temperature, pH, ions, enzymes, magnetic field, redox, etc., are explored. This article provides a review of five intensively studied types of stimuli-responsive peptides and proteins, their design principles and applications, including temperature-, pH-, light-, metal ion-, and enzyme-responsive with an emphasis on the key design concepts and switch function. Moreover, typical examples of their applications are discussed to provide a better understanding of the design concept and underlying methodology. This review will facilitate and inspire future innovation toward new peptide- and protein-based materials and their diverse applications.

Original language	English
Article number	2210387
Number of pages	31
Journal	Advanced Functional Materials
Volume	33
Issue number	7
DOIs	https://doi.org/10.1002/adfm.202210387
Publication status	Published - 9 Feb 2023

Keywords

light
metal ions
peptides
pH
proteins
stimuli-responsive behaviors
temperature

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10.1002/adfm.202210387Licence: CC BY-NC

Cite this

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abstract = "Stimuli-responsive peptides and proteins are an exciting class of smart biomaterials for various applications and have received significant attention over the past decades. A wide variety of stimuli such as temperature, pH, ions, enzymes, magnetic field, redox, etc., are explored. This article provides a review of five intensively studied types of stimuli-responsive peptides and proteins, their design principles and applications, including temperature-, pH-, light-, metal ion-, and enzyme-responsive with an emphasis on the key design concepts and switch function. Moreover, typical examples of their applications are discussed to provide a better understanding of the design concept and underlying methodology. This review will facilitate and inspire future innovation toward new peptide- and protein-based materials and their diverse applications.",

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author = "Yang Li and Guangze Yang and Lukas Gerstweiler and Thang, {San H.} and Zhao, {Chun Xia}",

note = "Funding Information: The authors acknowledge funding from the Australian Research Council for the ARC Centre of Excellence for Enabling Eco‐Efficient Beneficiation of Minerals (Grant No. CE200100009). Y.L. would like to thank the scholarship and stipend offered by the University of Queensland. C.‐X.Z. acknowledges the funding support from the National Health and Medical Research Council Investigator (Grant No. APP2008698). Funding Information: The authors acknowledge funding from the Australian Research Council for the ARC Centre of Excellence for Enabling Eco-Efficient Beneficiation of Minerals (Grant No. CE200100009). Y.L. would like to thank the scholarship and stipend offered by the University of Queensland. C.-X.Z. acknowledges the funding support from the National Health and Medical Research Council Investigator (Grant No. APP2008698). Open access publishing facilitated by The University of Adelaide, as part of the Wiley - The University of Adelaide agreement via the Council of Australian University Librarians. Publisher Copyright: {\textcopyright} 2022 The Authors. Advanced Functional Materials published by Wiley-VCH GmbH.",

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Design of Stimuli-Responsive Peptides and Proteins

Abstract

Keywords

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ARC Centre of Excellence for Enabling Eco-Efficient Beneficiation of Minerals

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