TY - JOUR
T1 - Depression, anxiety, and health related quality of life among colorectal cancer survivors
AU - Aminisani, Nayyereh
AU - Nikbakht, Hosseinali
AU - Jafarabadi, Mohammad Asghari
AU - Shamshirgaran, Seyed Morteza
N1 - Funding Information:
A substantial part of this study was funded by the research council, Tabriz University of Medical Sciences for which we are thankful. We extend our gratitude to staff working at the Babol cancer registry. We would also like to sincerely thank Mr. Habib Zadeh, Mr. Mirzad, Mrs. Mousavi, the staff at the Screening and Counselling Centre of Babol as well as all patients and their respective families who participated in this study.
Publisher Copyright:
© Journal of Gastrointestinal Oncology. All rights reserved.
PY - 2017
Y1 - 2017
N2 - Background: The aim of this study was to examine the relationship between psychological distress and quality of life (QOL) dimensions in colorectal cancer (CRC) patients. Methods: This cross-sectional study was conducted in the North of Iran. A total of 157 CRC survivors were selected from the registry database and included in this study. Psychological distress was measured using the Hospital Anxiety and Depression Scale (HADS) and QOL was estimated using the European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire C30 (EORTC QLQ C-30). The association between the patients' emotional functioning (EF) score on EORTC QLQ-C30 and their HADS scores was analysed through multiple linear regression. Results: In statistical terms, there were significantly negative relationships between EF and HADS-A (anxiety), and between HADS-D (depression) and HADS-T (total score). However, compared with HADS-A, the correlation between HADS-D and other QOL dimensions was significantly higher. By the same token, depression rather than anxiety was more strongly associated with reduced QOL. Conclusions: The EF dimension of the EORTC QLQ-C30 predominantly assesses anxiety; however, depression has a stronger impact on the global QOL of patients than anxiety. Therefore, the use of an additional instrument is recommended for the assessment of depression in outpatients with CRC.
AB - Background: The aim of this study was to examine the relationship between psychological distress and quality of life (QOL) dimensions in colorectal cancer (CRC) patients. Methods: This cross-sectional study was conducted in the North of Iran. A total of 157 CRC survivors were selected from the registry database and included in this study. Psychological distress was measured using the Hospital Anxiety and Depression Scale (HADS) and QOL was estimated using the European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire C30 (EORTC QLQ C-30). The association between the patients' emotional functioning (EF) score on EORTC QLQ-C30 and their HADS scores was analysed through multiple linear regression. Results: In statistical terms, there were significantly negative relationships between EF and HADS-A (anxiety), and between HADS-D (depression) and HADS-T (total score). However, compared with HADS-A, the correlation between HADS-D and other QOL dimensions was significantly higher. By the same token, depression rather than anxiety was more strongly associated with reduced QOL. Conclusions: The EF dimension of the EORTC QLQ-C30 predominantly assesses anxiety; however, depression has a stronger impact on the global QOL of patients than anxiety. Therefore, the use of an additional instrument is recommended for the assessment of depression in outpatients with CRC.
KW - Anxiety
KW - Colorectal cancer (CRC)
KW - Depression
KW - EORTC QLQ-C30
KW - Hospital Anxiety and Depression Scale (HADS)
KW - Quality of life (QOL)
UR - http://www.scopus.com/inward/record.url?scp=85014401181&partnerID=8YFLogxK
U2 - 10.21037/jgo.2017.01.12
DO - 10.21037/jgo.2017.01.12
M3 - Article
C2 - 28280612
AN - SCOPUS:85014401181
SN - 2078-6891
VL - 8
SP - 81
EP - 88
JO - Journal of Gastrointestinal Oncology
JF - Journal of Gastrointestinal Oncology
IS - 1
ER -
