TY - JOUR
T1 - Dehydroepiandrosterone sulfate and cognition in midlife, post-menopausal women
AU - Chua, Charlene K.Z.
AU - Henderson, Victor W.
AU - Dennerstein, Lorraine
AU - Ames, David
AU - Szoeke, Cassandra
PY - 2014/7
Y1 - 2014/7
N2 - The association between serum dehydroepiandrosterone sulfate (DHEAS) and cognition was assessed in 218 healthy, midlife, post-menopausal women, aged 55-65years. In cross-sectional analyses, DHEAS level was not significantly associated with a standardized score of global cognition or with individual test scores from a comprehensive neuropsychological battery (all p-values >0.05). In longitudinal analyses of 176 women, DHEAS level was unassociated with cognition 2years later or with 2-year change in cognition. These findings fail to support the view that DHEAS is substantially related to cognitive function in midlife, post-menopausal women.
AB - The association between serum dehydroepiandrosterone sulfate (DHEAS) and cognition was assessed in 218 healthy, midlife, post-menopausal women, aged 55-65years. In cross-sectional analyses, DHEAS level was not significantly associated with a standardized score of global cognition or with individual test scores from a comprehensive neuropsychological battery (all p-values >0.05). In longitudinal analyses of 176 women, DHEAS level was unassociated with cognition 2years later or with 2-year change in cognition. These findings fail to support the view that DHEAS is substantially related to cognitive function in midlife, post-menopausal women.
KW - Cognition
KW - Dehydroepiandrosterone sulfate
KW - Menopause
KW - Midlife
KW - Women
UR - http://www.scopus.com/inward/record.url?scp=84903371571&partnerID=8YFLogxK
U2 - 10.1016/j.neurobiolaging.2014.01.140
DO - 10.1016/j.neurobiolaging.2014.01.140
M3 - Article
C2 - 24612674
AN - SCOPUS:84903371571
SN - 0197-4580
VL - 35
SP - 1654
EP - 1655
JO - Neurobiology of Aging
JF - Neurobiology of Aging
IS - 7
ER -