Degradation of a lean magnesium alloy in simulated physiological condition for bioresorbable implant applications

Sanjay Mohan, Saad Al-Saadi, Shervin E. Harandi, Leopold Berger, Jörg F. Löffler, R. K. Singh Raman

Research output: Contribution to conferencePaper

Abstract

Biocompatible Mg-Zn-Ca alloys are an attractive candidate for biodegradable implant applications. However, it is necessary to consider the corrosion aspects of such alloys in properly simulated conditions to optimise and avoid their rapid degradation inside the human body. Corrosion of magnesium alloys can depend on metallurgical factors such as alloy composition, impurity content, grain size, texture, the presence of intermetallics and precipitates, and their shape and size. The in-vivo environmental factors such as the presence of proteins, temperature, pH, and flow need to be taken into account for an accurate determination of the corrosion rate of such biocompatible alloys in the human body. In the present investigation, the corrosion behaviour of an extruded, lean magnesium alloy, Mg-1wt%Zn-0.3wt%Ca (denominated as ZX10), was investigated in simulated human physiological conditions in the presence of both inorganic and organic constituents. Potentiodynamic polarization tests and electrochemical impedance spectroscopy were performed to investigate corrosion of the alloy in a typical Hank's solution, Hank's solution + albumin, and Hank's solution + albumin + glucose. The presence of albumin and Hank's solution + albumin + glucose was found to decrease the alloy's corrosion resistance.

Original languageEnglish
Number of pages9
Publication statusPublished - 2020
EventAustralasian Corrosion Association (ACA) Conference 2019 - Melbourne, Australia
Duration: 24 Nov 201927 Nov 2019

Conference

ConferenceAustralasian Corrosion Association (ACA) Conference 2019
CountryAustralia
CityMelbourne
Period24/11/1927/11/19

Keywords

  • Albumin
  • Bio-implants
  • Lean Mg alloy

Cite this

Mohan, S., Al-Saadi, S., Harandi, S. E., Berger, L., Löffler, J. F., & Singh Raman, R. K. (2020). Degradation of a lean magnesium alloy in simulated physiological condition for bioresorbable implant applications. Paper presented at Australasian Corrosion Association (ACA) Conference 2019, Melbourne, Australia.