Deformylation of indole and azaindole-3-carboxaldehydes using anthranilamide and solid acid heterogeneous catalyst via quinazolinone intermediate

Rammohan R. Yadav, Narsaiah Battini, Ramesh Mudududdla, Jaideep B. Bharate, Nagaraju Muparappu, Sandip B. Bharate, Ram A. Vishwakarma

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)


The deformylation of indole and azaindole-3-carboxaldehydes was achieved in the presence of anthranilamide and a solid acid heterogeneous catalyst under reflux conditions in 25-90% yield. The reaction proceeds via quinazolinone intermediate, which undergoes acid catalyzed cleavage to form deformylated product.

Original languageEnglish
Pages (from-to)2222-2225
Number of pages4
JournalTetrahedron Letters
Issue number17
Publication statusPublished - 25 Apr 2012
Externally publishedYes


  • Azaindole
  • Deformylation
  • Heterogeneous catalyst
  • Indole
  • Indole aldehyde
  • Quinazolinone

Cite this