TY - JOUR
T1 - Deep transcranial magnetic stimulation as a treatment for psychiatric disorders: A comprehensive review
AU - Bersani, F S
AU - Minichino, A
AU - Enticott, Peter Gregory
AU - Mazzarini, L
AU - Khan, N
AU - Antonacci, G
AU - Raccah, R N
AU - Salviati, M
AU - Chiaie, R Delle
AU - Bersani, G
AU - Fitzgerald, Paul Bernard
AU - Biondi, M
PY - 2013
Y1 - 2013
N2 - Deep transcranial magnetic stimulation (tms) is a technique of neuromodulation and neurostimulation based on the principle of electromagnetic induction of an electric field in the brain. The coil (h-coil) used in deep tms is able to modulate cortical excitability up to a maximum depth of 6. cm and is therefore able not only to modulate the activity of the cerebral cortex but also the activity of deeper neural circuits. Deep tms is largely used for the treatment of drug-resistant major depressive disorder (mdd) and is being tested to treat a very wide range of neurological, psychiatric and medical conditions. The aim of this review is to illustrate the biophysical principles of deep tms, to explain the pathophysiological basis for its utilization in each psychiatric disorder (major depression, autism, bipolar depression, auditory hallucinations, negative symptoms of schizophrenia), to summarize the results presented thus far in the international scientific literature regarding the use of deep tms in psychiatry, its side effects and its effects on cognitive functions.
AB - Deep transcranial magnetic stimulation (tms) is a technique of neuromodulation and neurostimulation based on the principle of electromagnetic induction of an electric field in the brain. The coil (h-coil) used in deep tms is able to modulate cortical excitability up to a maximum depth of 6. cm and is therefore able not only to modulate the activity of the cerebral cortex but also the activity of deeper neural circuits. Deep tms is largely used for the treatment of drug-resistant major depressive disorder (mdd) and is being tested to treat a very wide range of neurological, psychiatric and medical conditions. The aim of this review is to illustrate the biophysical principles of deep tms, to explain the pathophysiological basis for its utilization in each psychiatric disorder (major depression, autism, bipolar depression, auditory hallucinations, negative symptoms of schizophrenia), to summarize the results presented thus far in the international scientific literature regarding the use of deep tms in psychiatry, its side effects and its effects on cognitive functions.
UR - http://www.sciencedirect.com/science/article/pii/S0924933812000223
U2 - 10.1016/j.eurpsy.2012.02.006
DO - 10.1016/j.eurpsy.2012.02.006
M3 - Article
SN - 0924-9338
VL - 28
SP - 30
EP - 39
JO - European Psychiatry
JF - European Psychiatry
IS - 1
ER -