Decorated self-assembling β3-tripeptide foldamers form cell adhesive scaffolds

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Abstract

A popular strategy to control cellular growth and differentiation is the employment of self-assembling peptides as biomaterials. In this study we decorated ultrashort helical N-acetylated β-tripeptides with cell adhesion signals IKVAV and RGD, which spontaneously self-assemble to give nanofibres with multiple signals, and form a bioscaffold that supports the growth of cells.
Original languageEnglish
Pages (from-to)4549-4552
Number of pages4
JournalChemical Communications
Volume52
Issue number24
DOIs
Publication statusPublished - 29 Feb 2016

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