De novo synthesis of a potent LIMK1 inhibitor

Brad Sleebs; Ian Philip Street; Xian Bu; Jonathan Bayldon Baell

doi:10.1055/s-0029-1219230

De novo synthesis of a potent LIMK1 inhibitor

Brad Sleebs
, Ian Philip Street
, Xian Bu
, Jonathan Bayldon Baell

Research output: Contribution to journal › Article › Research › peer-review

12 Citations (Scopus)

Abstract

A potent LIMK1 inhibitor, BMS4, was synthesised in six steps starting from pyrazine-2-carboximidamide, offering a significant improvement over current methods available in the literature.

Original language	English
Pages (from-to)	1091 - 1096
Number of pages	6
Journal	Synthesis
Volume	7
DOIs	https://doi.org/10.1055/s-0029-1219230
Publication status	Published - 2010
Externally published	Yes

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title = "De novo synthesis of a potent LIMK1 inhibitor",

abstract = "A potent LIMK1 inhibitor, BMS4, was synthesised in six steps starting from pyrazine-2-carboximidamide, offering a significant improvement over current methods available in the literature.",

author = "Brad Sleebs and Street, \{Ian Philip\} and Xian Bu and Baell, \{Jonathan Bayldon\}",

year = "2010",

doi = "10.1055/s-0029-1219230",

language = "English",

volume = "7",

pages = "1091 -- 1096",

journal = "Synthesis",

issn = "0039-7881",

publisher = "Georg Thieme",

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AU - Sleebs, Brad

AU - Street, Ian Philip

AU - Bu, Xian

AU - Baell, Jonathan Bayldon

PY - 2010

Y1 - 2010

N2 - A potent LIMK1 inhibitor, BMS4, was synthesised in six steps starting from pyrazine-2-carboximidamide, offering a significant improvement over current methods available in the literature.

AB - A potent LIMK1 inhibitor, BMS4, was synthesised in six steps starting from pyrazine-2-carboximidamide, offering a significant improvement over current methods available in the literature.

UR - https://www.thieme-connect.de/ejournals/pdf/10.1055/s-0029-1219230.pdf

U2 - 10.1055/s-0029-1219230

DO - 10.1055/s-0029-1219230

M3 - Article

SN - 0039-7881

VL - 7

SP - 1091

EP - 1096

JO - Synthesis

JF - Synthesis

ER -

De novo synthesis of a potent LIMK1 inhibitor

Abstract

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