Data on the expression of cellular lncRNAs in human adenovirus infected cells

Maoshan Chen, Hongxing Zhao, Sara Bergström Lind, Ulf Pettersson

Research output: Contribution to journalArticleOtherpeer-review

6 Citations (Scopus)

Abstract

Expression of cellular long non-coding RNAs (lncRNAs) in human primary lung fibroblasts (IMR-90) during the course of adenovirus type 2 (Ad2) infection was studied by strand-specific whole transcriptome sequencing. In total, 645 cellular lncRNAs were expressed at a significant level and 398 of them were changed more than 2-fold. The changes in expression followed a distinct temporal pattern. Significantly, 80% of the changes occurred at the late phase and 80% of the de-regulated lncRNAs were up-regulated. The three largest groups of deregulated lncRNAs were 125 antisense RNAs, 111 pseudogenes and 85 long intergenic non-coding RNAs (lincRNAs). Lastly, more than 36% of lncRNAs have been shown to interact with RNA binding proteins.

Original languageEnglish
Pages (from-to)1263-1279
Number of pages17
JournalData in Brief
Volume8
DOIs
Publication statusPublished - 1 Sep 2016
Externally publishedYes

Keywords

  • Adenovirus
  • IMR-90
  • IncRNA
  • Long noncoding RNA

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