Cytokine-induced acute inflammatory monoarticular arthritis

Adrian Achuthan, Ming Chin Lee, Reem Saleh, Andrew J. Fleetwood, John A. Hamilton, Andrew D. Cook

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

2 Citations (Scopus)

Abstract

Animal models of arthritis enable us to investigate the pathogenesis of the disease and also to evaluate new therapies. Here we describe two different acute inflammatory monoarticular arthritis models (mBSA/IL1β and mBSA/GM-CSF) providing a more rapid and potentially simplified approach to investigate the pathogenesis.

Original languageEnglish
Title of host publicationMacrophages
Subtitle of host publicationMethods and Protocols
EditorsGermain Rousselet
Place of PublicationNew York NY USA
PublisherHumana Press
Chapter20
Pages215-223
Number of pages9
Volume1784
ISBN (Electronic)9781493978373
ISBN (Print)9781493978366
DOIs
Publication statusPublished - 2018
Externally publishedYes

Publication series

NameMethods in Molecular Biology
PublisherHumana Press
Volume1784
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • Arthritis animal models
  • Inflammatory arthritis
  • mBSA/GM-CSF
  • mBSA/IL1β
  • Rheumatoid arthritis

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