TY - JOUR
T1 - Análise cicitogenéticica em material de abortamento espontâneo
AU - Rolnik, Daniel Lorber
AU - de Carvalho, Mário Henrique Burlacchicchicchicchini
AU - Catelani, Ana Lúcicia Pereira Monteiro
AU - Pinto, Ana Paula Almeida Rochcha
AU - Lira, Juliana Branco Gonçalves
AU - Kusagari, Neusa Kiyomimi
AU - Belline, Paula
AU - Chauffaille, Maria de Lourdes
PY - 2010/12/1
Y1 - 2010/12/1
N2 - Objective. To describe chromosomal abnormalities in spontaneous abortion material. Methods. A retrospective compilation of karyotype analysis of slides stained with Band G was carried out by optical microscopy with materials of 428 abortion products referred for study. Results. There were 145 normal results (33.9%) and 237 abnormal results (55.4%). In 46 samples there was no cell growth (10.7%). Numerical abnormalities were the most frequent, especially trisomy 16 (41 cases), triplodia (27 cases), monosomy X (26 cases), tetraploidy (13 cases) and trisomy 15 (13 cases). Conclusion. Cytogenetic alterations are an important cause of pregnancy loss and their detection helps the genetic counseling to the couple. Trisomy 16 is the most often found change. [Rev Assoc Med Bras 2010; 56(6): 681-3].
AB - Objective. To describe chromosomal abnormalities in spontaneous abortion material. Methods. A retrospective compilation of karyotype analysis of slides stained with Band G was carried out by optical microscopy with materials of 428 abortion products referred for study. Results. There were 145 normal results (33.9%) and 237 abnormal results (55.4%). In 46 samples there was no cell growth (10.7%). Numerical abnormalities were the most frequent, especially trisomy 16 (41 cases), triplodia (27 cases), monosomy X (26 cases), tetraploidy (13 cases) and trisomy 15 (13 cases). Conclusion. Cytogenetic alterations are an important cause of pregnancy loss and their detection helps the genetic counseling to the couple. Trisomy 16 is the most often found change. [Rev Assoc Med Bras 2010; 56(6): 681-3].
KW - Abortion
KW - Chromosomal alterations
KW - Cytogenetics
UR - http://www.scopus.com/inward/record.url?scp=79551577696&partnerID=8YFLogxK
U2 - 10.1590/S0104-42302010000600017
DO - 10.1590/S0104-42302010000600017
M3 - Article
C2 - 21271135
AN - SCOPUS:79551577696
VL - 56
SP - 681
EP - 683
JO - Revista da Associacao Medica Brasileira
JF - Revista da Associacao Medica Brasileira
SN - 0104-4230
IS - 6
ER -