Análise cicitogenéticica em material de abortamento espontâneo

Translated title of the contribution: Cytogeneticic analysis of material from spontaneous abortion

Daniel Lorber Rolnik, Mário Henrique Burlacchicchicchicchini de Carvalho, Ana Lúcicia Pereira Monteiro Catelani, Ana Paula Almeida Rochcha Pinto, Juliana Branco Gonçalves Lira, Neusa Kiyomimi Kusagari, Paula Belline, Maria de Lourdes Chauffaille

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Abstract

Objective. To describe chromosomal abnormalities in spontaneous abortion material. Methods. A retrospective compilation of karyotype analysis of slides stained with Band G was carried out by optical microscopy with materials of 428 abortion products referred for study. Results. There were 145 normal results (33.9%) and 237 abnormal results (55.4%). In 46 samples there was no cell growth (10.7%). Numerical abnormalities were the most frequent, especially trisomy 16 (41 cases), triplodia (27 cases), monosomy X (26 cases), tetraploidy (13 cases) and trisomy 15 (13 cases). Conclusion. Cytogenetic alterations are an important cause of pregnancy loss and their detection helps the genetic counseling to the couple. Trisomy 16 is the most often found change. [Rev Assoc Med Bras 2010; 56(6): 681-3].

Translated title of the contributionCytogeneticic analysis of material from spontaneous abortion
Original languagePortuguese
Pages (from-to)681-683
Number of pages3
JournalRevista da Associacao Medica Brasileira
Volume56
Issue number6
DOIs
Publication statusPublished - 1 Dec 2010
Externally publishedYes

Keywords

  • Abortion
  • Chromosomal alterations
  • Cytogenetics

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