TY - JOUR
T1 - Current understanding of the role of B cell subsets and intimal and adventitial B cells in atherosclerosis
AU - Kyaw, Tin
AU - Tipping, Peter
AU - Toh, Ban-Hock
AU - Bobik, Alexander
PY - 2011
Y1 - 2011
N2 - Inflammation, in addition to high cholesterol is a major factor contributing to atherosclerosis-associated adverse cardiovascular events. Thus, there is a pressing need for additional therapeutic strategies to reduce inflammation, by targeting immune cells and cytokines. Here we review B cell subsets and adventitial and intimal B cells in atherosclerosis development and discuss potential B cell-targeted anti-inflammatory therapies for atherosclerosis.
AB - Inflammation, in addition to high cholesterol is a major factor contributing to atherosclerosis-associated adverse cardiovascular events. Thus, there is a pressing need for additional therapeutic strategies to reduce inflammation, by targeting immune cells and cytokines. Here we review B cell subsets and adventitial and intimal B cells in atherosclerosis development and discuss potential B cell-targeted anti-inflammatory therapies for atherosclerosis.
UR - http://www.ncbi.nlm.nih.gov/pubmed/21881498
U2 - 10.1097/MOL.0b013e32834adaf3
DO - 10.1097/MOL.0b013e32834adaf3
M3 - Article
SN - 0957-9672
VL - 22
SP - 373
EP - 379
JO - Current Opinion in Lipidology
JF - Current Opinion in Lipidology
IS - 5
ER -