Current understanding of the role of B cell subsets and intimal and adventitial B cells in atherosclerosis

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Abstract

Inflammation, in addition to high cholesterol is a major factor contributing to atherosclerosis-associated adverse cardiovascular events. Thus, there is a pressing need for additional therapeutic strategies to reduce inflammation, by targeting immune cells and cytokines. Here we review B cell subsets and adventitial and intimal B cells in atherosclerosis development and discuss potential B cell-targeted anti-inflammatory therapies for atherosclerosis.
Original languageEnglish
Pages (from-to)373 - 379
Number of pages7
JournalCurrent Opinion in Lipidology
Volume22
Issue number5
DOIs
Publication statusPublished - 2011

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