Current pattern of primary aldosteronism diagnosis

Delayed and complicated

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Background: Primary aldosteronism is the most common specifically treatable and potentially curable cause of hypertension.
Objective: The aim of this study was to analyse the referral pattern and disease characteristics of patients with hypertension and suspected primary aldosteronism.
Methods: We prospectively collected clinical data from patients who attended the Endocrine Hypertension Service (EHS) at Monash Health from May 2016 to May 2017.
Results: Of 87 patients, 69.2% had indications for primary aldosteronism screening in the primary care setting, although only 3.7% were actually screened. At the time of referral to the EHS, 61% had hypertension for over 10 years and 42% of the patients with primary aldosteronism had associated end-organ damage. Targeted treatment of primary aldosteronism led to biochemical and clinical improvement in all patients.
Discussion: The diagnosis of primary aldosteronism is currently delayed and associated with significant end-organ damage. Increased awareness of primary aldosteronism and its screening indications in primary and tertiary care is needed for earlier diagnosis and improved outcomes.
Original languageEnglish
Pages (from-to)712-718
Number of pages7
JournalAustralian Journal of General Practice
Volume47
Issue number10
Publication statusPublished - Oct 2018

Cite this

@article{8495ebba880d46a59882fc10f0b6fa20,
title = "Current pattern of primary aldosteronism diagnosis: Delayed and complicated",
abstract = "Background: Primary aldosteronism is the most common specifically treatable and potentially curable cause of hypertension. Objective: The aim of this study was to analyse the referral pattern and disease characteristics of patients with hypertension and suspected primary aldosteronism. Methods: We prospectively collected clinical data from patients who attended the Endocrine Hypertension Service (EHS) at Monash Health from May 2016 to May 2017. Results: Of 87 patients, 69.2{\%} had indications for primary aldosteronism screening in the primary care setting, although only 3.7{\%} were actually screened. At the time of referral to the EHS, 61{\%} had hypertension for over 10 years and 42{\%} of the patients with primary aldosteronism had associated end-organ damage. Targeted treatment of primary aldosteronism led to biochemical and clinical improvement in all patients. Discussion: The diagnosis of primary aldosteronism is currently delayed and associated with significant end-organ damage. Increased awareness of primary aldosteronism and its screening indications in primary and tertiary care is needed for earlier diagnosis and improved outcomes.",
author = "Lim, {Yin Yu} and Jimmy Shen and Fuller, {Peter J} and Jun Yang",
year = "2018",
month = "10",
language = "English",
volume = "47",
pages = "712--718",
journal = "Australian Journal of General Practice",
issn = "2208-7958",
publisher = "The Royal Australian College of General Practitioners",
number = "10",

}

Current pattern of primary aldosteronism diagnosis : Delayed and complicated. / Lim, Yin Yu; Shen, Jimmy; Fuller, Peter J; Yang, Jun.

In: Australian Journal of General Practice, Vol. 47, No. 10, 10.2018, p. 712-718.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Current pattern of primary aldosteronism diagnosis

T2 - Delayed and complicated

AU - Lim, Yin Yu

AU - Shen, Jimmy

AU - Fuller, Peter J

AU - Yang, Jun

PY - 2018/10

Y1 - 2018/10

N2 - Background: Primary aldosteronism is the most common specifically treatable and potentially curable cause of hypertension. Objective: The aim of this study was to analyse the referral pattern and disease characteristics of patients with hypertension and suspected primary aldosteronism. Methods: We prospectively collected clinical data from patients who attended the Endocrine Hypertension Service (EHS) at Monash Health from May 2016 to May 2017. Results: Of 87 patients, 69.2% had indications for primary aldosteronism screening in the primary care setting, although only 3.7% were actually screened. At the time of referral to the EHS, 61% had hypertension for over 10 years and 42% of the patients with primary aldosteronism had associated end-organ damage. Targeted treatment of primary aldosteronism led to biochemical and clinical improvement in all patients. Discussion: The diagnosis of primary aldosteronism is currently delayed and associated with significant end-organ damage. Increased awareness of primary aldosteronism and its screening indications in primary and tertiary care is needed for earlier diagnosis and improved outcomes.

AB - Background: Primary aldosteronism is the most common specifically treatable and potentially curable cause of hypertension. Objective: The aim of this study was to analyse the referral pattern and disease characteristics of patients with hypertension and suspected primary aldosteronism. Methods: We prospectively collected clinical data from patients who attended the Endocrine Hypertension Service (EHS) at Monash Health from May 2016 to May 2017. Results: Of 87 patients, 69.2% had indications for primary aldosteronism screening in the primary care setting, although only 3.7% were actually screened. At the time of referral to the EHS, 61% had hypertension for over 10 years and 42% of the patients with primary aldosteronism had associated end-organ damage. Targeted treatment of primary aldosteronism led to biochemical and clinical improvement in all patients. Discussion: The diagnosis of primary aldosteronism is currently delayed and associated with significant end-organ damage. Increased awareness of primary aldosteronism and its screening indications in primary and tertiary care is needed for earlier diagnosis and improved outcomes.

M3 - Article

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