TY - JOUR
T1 - Current management of patients with severe acute peripartum cardiomyopathy
T2 - practical guidance from the Heart Failure Association of the European Society of Cardiology Study Group on peripartum cardiomyopathy
AU - Bauersachs, Johann
AU - Arrigo, Mattia
AU - Hilfiker-Kleiner, Denise
AU - Veltmann, Christian
AU - Coats, Andrew J.S.
AU - Crespo-Leiro, Maria G.
AU - de Boer, Rudolf A
AU - van der Meer, Peter
AU - Maack, Christoph
AU - Mouquet, Frederic
AU - Petrie, Mark C
AU - Piepoli, Massimo F
AU - Regitz-Zagrosek, Vera
AU - Schaufelberger, Maria
AU - Seferovic, Petar M
AU - Tavazzi, Luigi
AU - Ruschitzka, Frank
AU - Mebazaa, Alexandre
AU - Sliwa, Karen
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Acute heart failure (AHF) due to peripartum cardiomyopathy (PPCM) provides a challenge for treating physicians. Moreover,in patients still pregnant, therapeutic interventions need always to consider the health of both the mother and the foetus. Especially challenging are severe forms of PPCM, as the mortality of these women is quite high. The use of inotropic drugs and mechanical circulatory support devices may be necessary in the initial phase of severe forms of acute PPCM. Many patients, after initial stabilization, recover LV function.1–3 Unfortunately, some patients need further mechanical circulatory support or urgent heart transplantation despite maximal therapy. In addition, the time frame and extent of recovery are unpredictable, and patients may suffer from cardiac arrest due to ventricular fibrillation in the first months after diagnosis.4 The clinical course may be further aggravated by atrial and/or ventricular thrombus formation with subsequent cardio-embolic complications.
AB - Acute heart failure (AHF) due to peripartum cardiomyopathy (PPCM) provides a challenge for treating physicians. Moreover,in patients still pregnant, therapeutic interventions need always to consider the health of both the mother and the foetus. Especially challenging are severe forms of PPCM, as the mortality of these women is quite high. The use of inotropic drugs and mechanical circulatory support devices may be necessary in the initial phase of severe forms of acute PPCM. Many patients, after initial stabilization, recover LV function.1–3 Unfortunately, some patients need further mechanical circulatory support or urgent heart transplantation despite maximal therapy. In addition, the time frame and extent of recovery are unpredictable, and patients may suffer from cardiac arrest due to ventricular fibrillation in the first months after diagnosis.4 The clinical course may be further aggravated by atrial and/or ventricular thrombus formation with subsequent cardio-embolic complications.
KW - Acute heart failure
KW - Initial management
KW - Mechanical circulatory support
KW - Medical therapy
KW - Peripartum cardiomyopathy
KW - Post-partum cardiomyopathy
KW - Sudden cardiac death
UR - http://www.scopus.com/inward/record.url?scp=84985937202&partnerID=8YFLogxK
U2 - 10.1002/ejhf.586
DO - 10.1002/ejhf.586
M3 - Article
AN - SCOPUS:84985937202
SN - 1388-9842
VL - 18
SP - 1096
EP - 1105
JO - European Journal of Heart Failure
JF - European Journal of Heart Failure
IS - 9
ER -