CT morphometry of adult thoracic intervertebral discs

Justin G.R. Fletcher, Mark D. Stringer, Christopher A. Briggs, Tilman M. Davies, Stephanie J. Woodley

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6 Citations (Scopus)

Abstract

Purpose: Despite being commonly affected by degenerative disorders, there are few data on normal thoracic intervertebral disc dimensions. A morphometric analysis of adult thoracic intervertebral discs was, therefore, undertaken. Methods: Archival computed tomography scans of 128 recently deceased individuals (70 males, 58 females, 20–79 years) with no known spinal pathology were analysed to determine thoracic disc morphometry and variations with disc level, sex and age. Reliability was assessed by intraclass correlation coefficients (ICCs). Results: Anterior and posterior intervertebral disc heights and axial dimensions were significantly greater in men (anterior disc height 4.0 ± 1.4 vs 3.6 ± 1.3 mm; posterior disc height 3.6 ± 0.90 vs 3.4 ± 0.93 mm; p < 0.01). Disc heights and axial dimensions at T4-5 were similar or smaller than at T2-3, but thereafter increased caudally (mean anterior disc height T4-5 and T10-11, 2.7 ± 0.7 and 5.4 ± 1.2 mm, respectively, in men; 2.6 ± 0.8 and 5.1 ± 1.3 mm, respectively, in women; p < 0.05). Except at T2-3, anterior disc height decreased with advancing age and anteroposterior and transverse disc dimensions increased; posterior and middle disc heights and indices of disc shape showed no consistent statistically significant changes. Most parameters showed substantial to almost perfect agreement for intra- and inter-rater reliability. Conclusions: Thoracic disc morphometry varies significantly and consistently with disc level, sex and age. This study provides unique reference data on adult thoracic intervertebral disc morphometry, which may be useful when interpreting pathological changes and for future biomechanical and functional studies.

Original languageEnglish
Pages (from-to)2321-2329
Number of pages9
JournalEuropean Spine Journal
Volume24
Issue number10
DOIs
Publication statusPublished - Oct 2015
Externally publishedYes

Keywords

  • Age
  • Computed tomography
  • Intervertebral disc
  • Morphometry
  • Thoracic spine

Cite this

Fletcher, J. G. R., Stringer, M. D., Briggs, C. A., Davies, T. M., & Woodley, S. J. (2015). CT morphometry of adult thoracic intervertebral discs. European Spine Journal, 24(10), 2321-2329. https://doi.org/10.1007/s00586-015-3925-y