TY - JOUR
T1 - CSA Is Not Beneficial Long Term in Heart Failure Patients with Reduced Ejection Fraction
AU - Oldenburg, Olaf
AU - Coats, Andrew
PY - 2017/1/15
Y1 - 2017/1/15
N2 - Central sleep apnea (CSA) affects many patients, with heart failure and results in hypoxia and nor-epinephrine release and is associated with high morbidity and mortality. Recent trials in the treatment of CSA using positive airway pressure therapies have failed to demonstrate improvement in mortality and as a result, the compensatory nature of CSA has been questioned. The detrimental effects from CSA are clear. While there may be a short term compensatory effect, the long term effects cause chronic insult to the cardiovascular system indicating that CSA should be treated, but alternative treatment options need to be considered.
AB - Central sleep apnea (CSA) affects many patients, with heart failure and results in hypoxia and nor-epinephrine release and is associated with high morbidity and mortality. Recent trials in the treatment of CSA using positive airway pressure therapies have failed to demonstrate improvement in mortality and as a result, the compensatory nature of CSA has been questioned. The detrimental effects from CSA are clear. While there may be a short term compensatory effect, the long term effects cause chronic insult to the cardiovascular system indicating that CSA should be treated, but alternative treatment options need to be considered.
KW - central sleep apnea
KW - compensatory mechanism
KW - heart failure
KW - sleep
UR - http://www.scopus.com/inward/record.url?scp=85003874701&partnerID=8YFLogxK
U2 - 10.1016/j.ijcard.2016.11.003
DO - 10.1016/j.ijcard.2016.11.003
M3 - Editorial
AN - SCOPUS:85003874701
VL - 227
SP - 474
EP - 477
JO - International Journal of Cardiology
JF - International Journal of Cardiology
SN - 0167-5273
ER -