Crystallization of an Lhx3-Isl1 complex

Mugdha Bhati, Mihwa Lee, Amy L Nancarrow, Ingolf Bach, J Mitchell Guss, Jacaqueline M Matthews

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Abstract

A stable intramolecular complex comprising the LIM domains of the LIM-homeodomain protein Lhx3 tethered to a peptide region of Isl1 has been engineered, purified and crystallized. The monoclinic crystals belong to space group C2, with unit-cell parameters a = 119, b = 62.2, c = 51.9 A, beta = 91.6 degrees , and diffract to 2.05 A resolution.
Original languageEnglish
Pages (from-to)297 - 299
Number of pages3
JournalActa Crystallographica Section F: Structural Biology Communications
Volume64
Issue numberPt. 4
DOIs
Publication statusPublished - 2008
Externally publishedYes

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