TY - JOUR
T1 - COVID-19 vaccinations
T2 - The unknowns, challenges, and hopes
AU - Mohamed, Kawthar
AU - Rzymski, Piotr
AU - Islam, Md Shahidul
AU - Makuku, Rangarirai
AU - Mushtaq, Ayesha
AU - Khan, Amjad
AU - Ivanovska, Mariya
AU - Makka, Sara A.
AU - Hashem, Fareeda
AU - Marquez, Leander
AU - Cseprekal, Orsolya
AU - Filgueiras, Igor Salerno
AU - Fonseca, Dennyson Leandro M.
AU - Mickael, Essouma
AU - Ling, Irene
AU - Arero, Amanuel Godana
AU - Cuschieri, Sarah
AU - Minakova, Kseniia
AU - Rodríguez-Román, Eduardo
AU - Abarikwu, Sunny O.
AU - Faten, Attig-Bahar
AU - Grancini, Giulia
AU - Cabral-Marques, Otavio
AU - Rezaei, Nima
N1 - Funding Information:
We acknowledge the São Paulo Research Foundation (FAPESP grants 2018/18886‐9, 2020/01688‐0, and 2020/07069‐0 to OCM) for financial support.
Publisher Copyright:
© 2021 Wiley Periodicals LLC.
PY - 2022/4
Y1 - 2022/4
N2 - The entire world has been suffering from the coronavirus disease 2019 (COVID-19) pandemic since March 11, 2020. More than a year later, the COVID-19 vaccination brought hope to control this viral pandemic. Here, we review the unknowns of the COVID-19 vaccination, such as its longevity, asymptomatic spread, long-term side effects, and its efficacy on immunocompromised patients. In addition, we discuss challenges associated with the COVID-19 vaccination, such as the global access and distribution of vaccine doses, adherence to hygiene guidelines after vaccination, the emergence of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, and vaccine resistance. Despite all these challenges and the fact that the end of the COVID-19 pandemic is still unclear, vaccines have brought great hope for the world, with several reports indicating a significant decline in the risk of COVID19-related infection and hospitalizations.
AB - The entire world has been suffering from the coronavirus disease 2019 (COVID-19) pandemic since March 11, 2020. More than a year later, the COVID-19 vaccination brought hope to control this viral pandemic. Here, we review the unknowns of the COVID-19 vaccination, such as its longevity, asymptomatic spread, long-term side effects, and its efficacy on immunocompromised patients. In addition, we discuss challenges associated with the COVID-19 vaccination, such as the global access and distribution of vaccine doses, adherence to hygiene guidelines after vaccination, the emergence of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, and vaccine resistance. Despite all these challenges and the fact that the end of the COVID-19 pandemic is still unclear, vaccines have brought great hope for the world, with several reports indicating a significant decline in the risk of COVID19-related infection and hospitalizations.
KW - COVID-19
KW - COVID-19 vaccination
KW - global assessment
KW - global challenges
KW - herd immunity
KW - SARS-CoV-2
UR - https://www.scopus.com/pages/publications/85120910805
U2 - 10.1002/jmv.27487
DO - 10.1002/jmv.27487
M3 - Review Article
C2 - 34845731
AN - SCOPUS:85120910805
SN - 0146-6615
VL - 94
SP - 1336
EP - 1349
JO - Journal of Medical Virology
JF - Journal of Medical Virology
IS - 4
ER -
SDG 3 Good Health and Well-being